Diabetes Mellitus, Insulin-Dependent

GPTKB entity

Statements (50)
Predicate Object
gptkbp:instanceOf gptkb:disease
gptkbp:abbreviation gptkb:IDDM
gptkbp:affects adults
children
pancreas
endocrine system
gptkbp:alsoKnownAs gptkb:Type_1_Diabetes_Mellitus
gptkbp:associatedWith gptkb:HLA-DR4
autoantibodies
HLA-DR3
gptkbp:canBeComplicatedBy gptkb:cardiovascular_disease
stroke
peripheral vascular disease
gptkbp:cannotBeTreatedWith oral hypoglycemic agents
gptkbp:cause gptkb:hypoglycemia
hyperglycemia
gptkbp:causedBy obesity
lifestyle factors
autoimmune destruction of pancreatic beta cells
gptkbp:complication gptkb:diabetic_ketoacidosis
gptkb:nephropathy
peripheral neuropathy
retinopathy
gptkbp:diagnosedBy HbA1c test
fasting blood glucose
gptkbp:firstDescribed 19th century
gptkbp:hasBiomarker GAD antibodies
C-peptide (low or absent)
islet cell antibodies
https://www.w3.org/2000/01/rdf-schema#label Diabetes Mellitus, Insulin-Dependent
gptkbp:ICD-10_code E10
gptkbp:managedBy physical activity
dietary management
blood glucose monitoring
gptkbp:onset childhood
adolescence
gptkbp:prevalence less common than Type 2 Diabetes
gptkbp:primaryTreatment insulin therapy
gptkbp:requires lifelong management
gptkbp:riskFactor family history
genetic predisposition
gptkbp:subspecies Juvenile Diabetes
Latent Autoimmune Diabetes in Adults
gptkbp:symptom weight loss
polydipsia
polyuria
polyphagia
gptkbp:bfsParent gptkb:D004053
gptkb:D004481
gptkbp:bfsLayer 7