Diabetes Mellitus, Insulin-Dependent

GPTKB entity

Predicate	Object
gptkbp:instanceOf	gptkb:disease
gptkbp:abbreviation	gptkb:IDDM
gptkbp:affects	adults children pancreas endocrine system
gptkbp:alsoKnownAs	gptkb:Type_1_Diabetes_Mellitus
gptkbp:associatedWith	gptkb:HLA-DR4 autoantibodies HLA-DR3
gptkbp:canBeComplicatedBy	gptkb:cardiovascular_disease stroke peripheral vascular disease
gptkbp:cannotBeTreatedWith	oral hypoglycemic agents
gptkbp:cause	gptkb:hypoglycemia hyperglycemia
gptkbp:causedBy	obesity lifestyle factors autoimmune destruction of pancreatic beta cells
gptkbp:complication	gptkb:peripheral_neuropathy gptkb:diabetic_ketoacidosis gptkb:nephropathy retinopathy
gptkbp:diagnosedBy	HbA1c test fasting blood glucose
gptkbp:firstDescribed	gptkb:19th_century
gptkbp:hasBiomarker	GAD antibodies C-peptide (low or absent) islet cell antibodies
gptkbp:ICD-10_code	E10
gptkbp:managedBy	gptkb:physical_activity dietary management blood glucose monitoring
gptkbp:onset	childhood adolescence
gptkbp:prevalence	less common than Type 2 Diabetes
gptkbp:primaryTreatment	insulin therapy
gptkbp:requires	lifelong management
gptkbp:riskFactor	family history genetic predisposition
gptkbp:subspecies	Juvenile Diabetes Latent Autoimmune Diabetes in Adults
gptkbp:symptom	weight loss polydipsia polyuria polyphagia
gptkbp:bfsParent	gptkb:D004053
gptkbp:bfsLayer	7
https://www.w3.org/2000/01/rdf-schema#label	Diabetes Mellitus, Insulin-Dependent