Diabetes Mellitus, Insulin-Dependent
GPTKB entity
Statements (50)
Predicate | Object |
---|---|
gptkbp:instanceOf |
gptkb:disease
|
gptkbp:abbreviation |
gptkb:IDDM
|
gptkbp:affects |
adults
children pancreas endocrine system |
gptkbp:alsoKnownAs |
gptkb:Type_1_Diabetes_Mellitus
|
gptkbp:associatedWith |
gptkb:HLA-DR4
autoantibodies HLA-DR3 |
gptkbp:canBeComplicatedBy |
gptkb:cardiovascular_disease
stroke peripheral vascular disease |
gptkbp:cannotBeTreatedWith |
oral hypoglycemic agents
|
gptkbp:cause |
gptkb:hypoglycemia
hyperglycemia |
gptkbp:causedBy |
obesity
lifestyle factors autoimmune destruction of pancreatic beta cells |
gptkbp:complication |
gptkb:diabetic_ketoacidosis
gptkb:nephropathy peripheral neuropathy retinopathy |
gptkbp:diagnosedBy |
HbA1c test
fasting blood glucose |
gptkbp:firstDescribed |
19th century
|
gptkbp:hasBiomarker |
GAD antibodies
C-peptide (low or absent) islet cell antibodies |
https://www.w3.org/2000/01/rdf-schema#label |
Diabetes Mellitus, Insulin-Dependent
|
gptkbp:ICD-10_code |
E10
|
gptkbp:managedBy |
physical activity
dietary management blood glucose monitoring |
gptkbp:onset |
childhood
adolescence |
gptkbp:prevalence |
less common than Type 2 Diabetes
|
gptkbp:primaryTreatment |
insulin therapy
|
gptkbp:requires |
lifelong management
|
gptkbp:riskFactor |
family history
genetic predisposition |
gptkbp:subspecies |
Juvenile Diabetes
Latent Autoimmune Diabetes in Adults |
gptkbp:symptom |
weight loss
polydipsia polyuria polyphagia |
gptkbp:bfsParent |
gptkb:D004053
gptkb:D004481 |
gptkbp:bfsLayer |
7
|