Statements (43)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:drug
|
| gptkbp:ATCCode |
A03AE01
|
| gptkbp:bioavailability |
10%
|
| gptkbp:CASNumber |
189188-57-6
|
| gptkbp:category |
serotonin receptor agonist
gastroprokinetic agent |
| gptkbp:contraindication |
severe renal impairment
severe hepatic impairment history of bowel obstruction ischemic colitis |
| gptkbp:drugClass |
increases gastrointestinal motility
|
| gptkbp:eliminationHalfLife |
11 hours
|
| gptkbp:excretion |
urine
feces |
| gptkbp:hasInChIKey |
QYJXJQFZJZTXHB-IZZDOVSWSA-N
|
| gptkbp:hasMolecularFormula |
C16H19N3O3S
|
| gptkbp:hasReintroduction |
restricted access program (US, 2008)
|
| gptkbp:hasSMILES |
CCCCCNS(=O)(=O)C1=CC=C(C=C1OC)N=CC2=CN=CN2C
|
| gptkbp:hasUNII |
K8L3F7C5PO
|
| https://www.w3.org/2000/01/rdf-schema#label |
DB08604
|
| gptkbp:indication |
chronic idiopathic constipation
irritable bowel syndrome with constipation |
| gptkbp:isWithdrawn |
yes
|
| gptkbp:IUPACName |
(Z)-5-methoxy-2-[(5-methyl-1H-imidazol-4-yl)methyleneamino]-N-pentylbenzene-1-sulfonamide
|
| gptkbp:legalStatus |
prescription only
|
| gptkbp:manufacturer |
gptkb:Novartis
|
| gptkbp:mechanismOfAction |
5-HT4 receptor partial agonist
|
| gptkbp:metabolism |
hepatic
|
| gptkbp:molecularWeight |
333.41
|
| gptkbp:pregnancyCategory |
B (US)
|
| gptkbp:proteinBinding |
98%
|
| gptkbp:PubChem_CID |
gptkb:DB08604
CHEMBL1201192 159869 D04719 |
| gptkbp:routeOfAdministration |
oral
|
| gptkbp:sideEffect |
diarrhea
abdominal pain headache |
| gptkbp:status |
yes
|
| gptkbp:synonym |
Tegaserod
|
| gptkbp:bfsParent |
gptkb:triclosan
|
| gptkbp:bfsLayer |
7
|