Statements (62)
| Predicate | Object |
|---|---|
| gptkbp:instance_of |
gptkb:physicist
|
| gptkbp:advocates_for |
gptkb:Cystic_Fibrosis_Foundation
|
| gptkbp:affects |
digestive system
lungs |
| gptkbp:associated_with |
gptkb:Company
infertility in males pancreatic insufficiency |
| gptkbp:caused_by |
mutation in the CFTR gene
mutations in CFTR gene |
| gptkbp:clinical_trial |
ongoing
|
| gptkbp:collaborations |
increasing among institutions
|
| gptkbp:community_impact |
financial burden
significant emotional burden |
| gptkbp:community_involvement |
important for support
|
| gptkbp:community_support |
strong
|
| gptkbp:complications |
malnutrition
liver disease lung damage intestinal blockages |
| gptkbp:descendant |
autosomal recessive pattern
|
| gptkbp:economic_impact |
can be challenging
|
| gptkbp:education |
can be challenging
|
| gptkbp:first_described_by |
1938
|
| gptkbp:frequency |
1 in 25 individuals of European descent
|
| gptkbp:function |
regulates salt and water movement
|
| gptkbp:genetic_diversity |
recommended for families
|
| gptkbp:habitat |
chromosome 7
|
| https://www.w3.org/2000/01/rdf-schema#label |
Cystic Fibrosis
|
| gptkbp:impact |
gptkb:significant
|
| gptkbp:is_a_resource_for |
gptkb:stock_market_index
|
| gptkbp:is_often_used_in |
Caucasian populations
|
| gptkbp:is_popular_in |
varies by ethnicity
1 in 3,500 births in the United States |
| gptkbp:lifespan |
improving over time
mid-40s to early 50s |
| gptkbp:named_after |
the cystic fibrosis of the pancreas
|
| gptkbp:public_awareness |
important
|
| gptkbp:receives_funding_from |
increasing
|
| gptkbp:research_focus |
gptkb:physicist
new medications improved lung function |
| gptkbp:scholarships |
gptkb:stock_market_index
|
| gptkbp:screenings |
newborns
|
| gptkbp:side_effect |
gptkb:significant
|
| gptkbp:social_responsibility |
genetic testing
sweat test |
| gptkbp:symptoms |
frequent lung infections
shortness of breath chronic cough poor growth salty skin essential for quality of life |
| gptkbp:treatment |
improved outcomes
personalized medicine new therapies lung transplant chest physiotherapy enzyme supplements inhaled medications |
| gptkbp:type_of_care |
recommended
|
| gptkbp:bfsParent |
gptkb:Vertex_Pharmaceuticals
|
| gptkbp:bfsLayer |
3
|