Statements (50)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
medical condition
genetic disorder |
| gptkbp:affects |
infants
skull multiple sutures one suture |
| gptkbp:associatedWith |
gptkb:Muenke_syndrome
gptkb:Apert_syndrome gptkb:Crouzon_syndrome gptkb:Pfeiffer_syndrome airway obstruction hydrocephalus midface hypoplasia Chiari malformation |
| gptkbp:canBe |
inherited
sporadic isolated syndromic |
| gptkbp:cause |
vision problems
hearing loss learning disabilities seizures increased intracranial pressure speech delay developmental delays facial asymmetry abnormal head shape neurocognitive impairment premature fusion of cranial sutures |
| gptkbp:detects |
gptkb:CT_scan
MRI prenatal ultrasound |
| gptkbp:diagnosedBy |
physical examination
imaging studies |
| gptkbp:firstDescribed |
19th century
|
| https://www.w3.org/2000/01/rdf-schema#label |
Craniosynostosis
|
| gptkbp:ICD-10_code |
Q75.0
|
| gptkbp:prevalence |
about 1 in 2,000 live births
|
| gptkbp:riskFactor |
family history
genetic syndromes |
| gptkbp:subspecies |
coronal synostosis
lambdoid synostosis metopic synostosis sagittal synostosis |
| gptkbp:treatment |
surgery
endoscopic surgery cranial vault remodeling |
| gptkbp:bfsParent |
gptkb:Craniofacial_Growth
gptkb:Distraction_osteogenesis |
| gptkbp:bfsLayer |
6
|