Corey– Mitsunobu reaction
GPTKB entity
Statements (66)
| Predicate | Object |
|---|---|
| gptkbp:instance_of |
gptkb:chemical_compound
|
| gptkbp:applies_to |
alcohols
amines carboxylic acids |
| gptkbp:can_create |
stereocenters
|
| gptkbp:challenges |
certain substrates
|
| gptkbp:collaborated_with |
research projects
|
| gptkbp:developed_by |
gptkb:E._J._Corey
gptkb:T._Mitsunobu |
| gptkbp:first_described_by |
gptkb:1981
|
| https://www.w3.org/2000/01/rdf-schema#label |
Corey– Mitsunobu reaction
|
| gptkbp:involves |
nucleophilic substitution
azodicarboxylate phosphine reagents |
| gptkbp:is_analyzed_in |
mechanistic studies
|
| gptkbp:is_applied_in |
complex molecules
|
| gptkbp:is_associated_with |
gptkb:E._J._Corey
gptkb:T._Mitsunobu |
| gptkbp:is_challenged_by |
side reactions
|
| gptkbp:is_cited_in |
academic papers
|
| gptkbp:is_compared_to |
other alkylation methods
|
| gptkbp:is_considered_as |
a powerful tool
a key reaction |
| gptkbp:is_discussed_in |
gptkb:textbooks
|
| gptkbp:is_documented_in |
gptkb:literature
patents |
| gptkbp:is_enhanced_by |
new reagents
|
| gptkbp:is_evaluated_by |
industrial processes
|
| gptkbp:is_explored_in |
research articles
new applications |
| gptkbp:is_featured_in |
conferences
|
| gptkbp:is_influenced_by |
advancements in chemistry
|
| gptkbp:is_known_for |
high stereoselectivity
|
| gptkbp:is_notable_for |
its versatility
|
| gptkbp:is_noted_for |
its selectivity
its broad applicability its high yields its mild conditions |
| gptkbp:is_optimized_for |
specific substrates
|
| gptkbp:is_part_of |
reaction mechanisms
|
| gptkbp:is_promoted_by |
chemical societies
|
| gptkbp:is_recognized_for |
its efficiency
|
| gptkbp:is_recommended_by |
other methods for certain substrates
|
| gptkbp:is_related_to |
Mitsunobu reaction
|
| gptkbp:is_reviewed_by |
chemical reviews
|
| gptkbp:is_significant_for |
organic synthesis
|
| gptkbp:is_studied_in |
mechanistic chemistry
|
| gptkbp:is_supported_by |
funding agencies
computational chemistry |
| gptkbp:is_taught_in |
organic chemistry courses
|
| gptkbp:is_used_in |
pharmaceutical chemistry
total synthesis natural product synthesis |
| gptkbp:is_used_to |
create ethers
form amines modify alcohols |
| gptkbp:is_utilized_by |
synthetic chemists
|
| gptkbp:produces |
alkylated product
|
| gptkbp:requires |
a phosphine
an alcohol an azodicarboxylate |
| gptkbp:used_for |
inversion of configuration at a stereogenic center
|
| gptkbp:was_a_catalyst_for |
phosphine
diethyl azodicarboxylate |
| gptkbp:bfsParent |
gptkb:Elias_James_Corey
|
| gptkbp:bfsLayer |
5
|