Statements (48)
Predicate | Object |
---|---|
gptkbp:instanceOf |
peptide
|
gptkbp:abbreviation |
gptkb:CCK
|
gptkbp:aminoAcidSequence |
varies (CCK-8, CCK-33, CCK-58, etc.)
|
gptkbp:category |
digestive system
hormone peptide |
gptkbp:discoveredBy |
gptkb:Ivy_and_Oldberg
|
gptkbp:discoveredIn |
1928
|
gptkbp:effect |
increases bile flow
induces satiety modulates anxiety modulates pain perception reduces food intake slows gastric emptying stimulates gallbladder contraction stimulates pancreatic enzyme secretion |
gptkbp:function |
modulation of anxiety
modulation of pain regulation of digestion satiety signaling |
gptkbp:gene |
gptkb:CCK_gene
|
https://www.w3.org/2000/01/rdf-schema#label |
Cholecystokinin
|
gptkbp:inhibitedBy |
food intake
gastric emptying |
gptkbp:location |
gptkb:small_intestine
central nervous system |
gptkbp:medicalUse |
diagnosis of pancreatic function
diagnosis of gallbladder function research in satiety and obesity |
gptkbp:predecessor |
gptkb:preprocholecystokinin
|
gptkbp:producedBy |
gptkb:duodenum
jejunum neurons in the brain |
gptkbp:promotion |
amino acids in duodenum
fatty acids in duodenum gallbladder contraction pancreatic enzyme secretion |
gptkbp:recipient |
gptkb:CCK-A_receptor
gptkb:CCK-B_receptor |
gptkbp:relatedTo |
gptkb:gastrin
|
gptkbp:role |
bile secretion
appetite regulation brain signaling gastrointestinal motility pancreatic secretion |
gptkbp:structure |
peptide
|
gptkbp:bfsParent |
gptkb:CCK
|
gptkbp:bfsLayer |
5
|