|
gptkbp:instanceOf
|
disinfectant
|
|
gptkbp:ATCCode
|
D08AC02
|
|
gptkbp:brand
|
gptkb:Corsodyl
gptkb:Hibiclens
gptkb:Peridex
|
|
gptkbp:CASNumber
|
55-56-1
|
|
gptkbp:chemical_compound
|
C22H30Cl2N10
|
|
gptkbp:contraindication
|
hypersensitivity to chlorhexidine
|
|
gptkbp:discoveredBy
|
gptkb:Imperial_Chemical_Industries
|
|
gptkbp:discoveredIn
|
1950
|
|
gptkbp:effect
|
Gram-negative bacteria
Gram-positive bacteria
|
|
gptkbp:excretion
|
feces
urine (minor)
|
|
gptkbp:form
|
gptkb:butter
gptkb:government_agency
toothpaste
gel
wipes
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Chlorhexidine
|
|
gptkbp:includedIn
|
gptkb:WHO_List_of_Essential_Medicines
|
|
gptkbp:legalStatus
|
gptkb:OTC
|
|
gptkbp:mechanismOfAction
|
disrupts microbial cell membranes
|
|
gptkbp:meltingPoint
|
134-136°C
|
|
gptkbp:metabolism
|
not significantly metabolized
|
|
gptkbp:molecularWeight
|
505.45 g/mol
|
|
gptkbp:notEffectiveAgainst
|
bacterial spores
mycobacteria
non-enveloped viruses
|
|
gptkbp:pregnancyCategory
|
B (US)
|
|
gptkbp:PubChem_CID
|
7996
9552079
CHEBI:3644
|
|
gptkbp:routeOfAdministration
|
oral
topical
intravenous (rare)
|
|
gptkbp:sideEffect
|
skin irritation
allergic reactions
taste alteration
tooth staining
|
|
gptkbp:solubility
|
slightly soluble in water
|
|
gptkbp:spectrumOfActivity
|
broad-spectrum
|
|
gptkbp:UNII
|
O0G383GSIK
|
|
gptkbp:usedFor
|
wound cleaning
dental plaque control
oral rinse
preoperative skin preparation
skin disinfection
|
|
gptkbp:bfsParent
|
gptkb:CHC
|
|
gptkbp:bfsLayer
|
6
|