Charcot–Marie–Tooth disease

GPTKB entity

Predicate	Object
gptkbp:instanceOf	gptkb:muscular_dystrophy gptkb:hereditary_spastic_paraplegia gptkb:rare_disease
gptkbp:affects	peripheral nerves
gptkbp:alsoKnownAs	gptkb:CMT
gptkbp:cause	gptkb:genetic_disorder
gptkbp:complication	chronic pain difficulty walking loss of mobility deformities of feet and hands
gptkbp:diagnosedBy	genetic testing clinical examination nerve conduction study
gptkbp:field	genetics neurology
gptkbp:firstDescribed	1886
gptkbp:frequency	1 in 2,500 people
gptkbp:ICD-10_code	gptkb:G60.0
gptkbp:inheritance	autosomal dominant autosomal recessive X-linked
gptkbp:MeSH_ID	D002786
gptkbp:namedAfter	gptkb:Pierre_Marie gptkb:Jean-Martin_Charcot gptkb:Howard_Henry_Tooth
gptkbp:OMIM	118220
gptkbp:onset	childhood adolescence early adulthood
gptkbp:prevalence	commonest inherited neurological disorder
gptkbp:subspecies	gptkb:CMT1 gptkb:CMT2 gptkb:CMT3 gptkb:CMT4 gptkb:CMTX
gptkbp:symptom	muscle atrophy muscle weakness loss of sensation foot drop claw toes high arched feet
gptkbp:treatment	orthopedic surgery occupational therapy physical therapy pain management orthopedic devices
gptkbp:bfsParent	gptkb:Pierre_Marie gptkb:Victor_Bailey
gptkbp:bfsLayer	6
https://www.w3.org/2000/01/rdf-schema#label	Charcot–Marie–Tooth disease