Canakinumab Anti-inflammatory Thrombosis Outcomes Study

GPTKB entity

Statements (23)
Predicate Object
gptkbp:instanceOf gptkb:clinical_trial
gptkbp:abbreviation gptkb:CANTOS
gptkbp:clinicalTrials.govIdentifier gptkb:NCT01327846
gptkbp:controls placebo
gptkbp:enrollment over 10,000 patients
gptkbp:foundIn canakinumab reduced recurrent cardiovascular events
canakinumab increased risk of fatal infection
canakinumab reduced inflammation (CRP levels)
https://www.w3.org/2000/01/rdf-schema#label Canakinumab Anti-inflammatory Thrombosis Outcomes Study
gptkbp:intervention canakinumab 150 mg
canakinumab 300 mg
canakinumab 50 mg
gptkbp:location international
gptkbp:population patients with prior myocardial infarction
gptkbp:publicationYear 2017
gptkbp:publishedIn gptkb:New_England_Journal_of_Medicine
gptkbp:result cardiovascular event reduction
gptkbp:sponsor gptkb:Novartis
gptkbp:startYear 2011
gptkbp:studiedDrug gptkb:canakinumab
gptkbp:studyType gptkb:clinical_trial
gptkbp:bfsParent gptkb:CANTOS_trial
gptkbp:bfsLayer 6