Statements (53)
Predicate | Object |
---|---|
gptkbp:instance_of |
gptkb:vaccine
|
gptkbp:bfsLayer |
4
|
gptkbp:bfsParent |
gptkb:Albert_Calmette
|
gptkbp:age |
infants
|
gptkbp:allows |
may cause false-positive tuberculin skin tests
not recommended for certain populations not universally effective requires trained personnel for administration |
gptkbp:appointed_by |
intradermal injection
|
gptkbp:approves |
many countries
|
gptkbp:brand |
gptkb:BCG
|
gptkbp:category |
BCG vaccine
|
gptkbp:clinical_trial |
ongoing research
|
gptkbp:contraindication |
pregnancy
immunocompromised individuals |
gptkbp:developed_by |
gptkb:Camille_Guérin
gptkb:Albert_Calmette |
gptkbp:dosage_form |
single dose
|
gptkbp:first_introduced |
gptkb:1921
|
gptkbp:global_presence |
over 100 countries
|
gptkbp:historical_significance |
first vaccine for tuberculosis
|
https://www.w3.org/2000/01/rdf-schema#label |
Calmette-Guérin vaccine
|
gptkbp:impact |
tuberculosis incidence
|
gptkbp:is_effective_against |
varies by population
|
gptkbp:is_used_for |
tuberculosis prevention
|
gptkbp:is_vulnerable_to |
preventive vaccine
developed from Mycobacterium bovis 50-80% in preventing severe forms of tuberculosis analyzed for long-term effects assessed for efficacy in elderly populations evaluated for safety in pregnancy explored for combination therapies explored for use in COVID-19 trials investigated for use in HIV patients investigated for use in other cancers less effective against pulmonary tuberculosis reduces risk of disseminated tuberculosis reduces risk of tuberculosis meningitis studied for immune modulation studied for potential in autoimmune diseases improves overall survival in bladder cancer patients |
gptkbp:part_of |
tuberculosis control programs
|
gptkbp:produced_by |
various pharmaceutical companies
|
gptkbp:research_focus |
bladder cancer treatment
immune response enhancement |
gptkbp:side_effect |
fever
lymphadenopathy local reactions |
gptkbp:social_responsibility |
tuberculosis
bladder cancer |
gptkbp:storage |
refrigeration
|
gptkbp:suitable_for |
gptkb:WHO
|
gptkbp:type |
live attenuated vaccine
|