Statements (64)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gene
|
| gptkbp:alias |
gptkb:Bcl11b
|
| gptkbp:associatedWith |
immune response
autoimmune diseases chronic inflammation viral infections T-cell malignancies lymphoma inflammatory diseases graft-versus-host disease chronic infections |
| gptkbp:bornIn |
bone marrow
hematopoietic cells peripheral blood lymphocytes |
| gptkbp:breedingSeason |
protein-coding gene
|
| gptkbp:clinicalTrials |
potential biomarker
|
| gptkbp:code |
gptkb:CTIP3_protein
|
| gptkbp:community |
cytokines
tissue-specific transcriptional enhancers upregulated in activated T-cells |
| gptkbp:conservationEfforts |
vertebrates
|
| gptkbp:culturalEvents |
CTIP3_in_other_species
|
| gptkbp:fossilRecord |
biological process
|
| gptkbp:function |
transcriptional regulation
|
| gptkbp:geneticDiversity |
chromosome 10
immunodeficiency zinc finger proteins |
| https://www.w3.org/2000/01/rdf-schema#label |
CTIP3 gene
|
| gptkbp:influences |
T-cell activation
cytokine production immune response pathways immune cell signaling |
| gptkbp:interactsWith |
other transcription factors
|
| gptkbp:involvedIn |
immune tolerance
T-cell development immune checkpoint regulation lymphocyte differentiation |
| gptkbp:is_a_route_for |
T-cell receptor signaling pathway
|
| gptkbp:is_evaluated_by |
thymus
|
| gptkbp:isActiveIn |
apoptosis in T-cells
|
| gptkbp:level |
varies in tissues
|
| gptkbp:linkedTo |
immune evasion mechanisms
autoimmune disorders chronic lymphocytic leukemia T-regulatory cells |
| gptkbp:locatedIn |
mice
human genome |
| gptkbp:promotes |
T-cell survival
|
| gptkbp:regulates |
gene expression
|
| gptkbp:regulatoryCompliance |
DNA binding
|
| gptkbp:relatedTo |
transcription factors
|
| gptkbp:research |
clinical trials
therapeutic interventions therapeutic targets gene therapy approaches transgenic models gene knockout models |
| gptkbp:researchFocus |
immunology
|
| gptkbp:researchInterest |
CRISPR gene editing
cancer studies vaccine development role in cancer progression |
| gptkbp:supportRole |
immune system modulation
|