Statements (65)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
cell line
|
| gptkbp:are |
used in drug discovery
used in toxicology studies a key component in biomanufacturing a key tool in molecular biology a model for studying cancer biology a model for studying protein interactions a model system for human biology a platform for drug development a source of glycoproteins a source of therapeutic proteins. a standard in cell culture a standard model for mammalian cells immortalized cell lines important for biopharmaceutical development important for vaccine development used for studying cell signaling used in antibody engineering used in cell-based assays used in monoclonal antibody production used in the production of enzymes used in the production of monoclonal antibodies used in the production of vaccines used in the study of cellular responses used in the study of gene regulation used in the study of metabolic pathways eukaryotic_cells non-tumorigenic |
| gptkbp:built |
gptkb:Chinese_hamster_ovaries
|
| gptkbp:canBe |
high-throughput screening
bioreactors recombinant proteins serum-free media |
| gptkbp:canCreate |
viral vectors
yield of protein production |
| gptkbp:characterizedBy |
high growth rate
|
| gptkbp:exhibits |
adaptability to suspension culture
|
| gptkbp:has |
a diploid genome
|
| gptkbp:hasRelatedPatent |
vaccine production
|
| https://www.w3.org/2000/01/rdf-schema#label |
CHO cells
|
| gptkbp:is_used_in |
pharmaceutical industry
protein production |
| gptkbp:isCitedIn |
liquid nitrogen
|
| gptkbp:isEnhancedBy |
cell growth
|
| gptkbp:isEvaluatedBy |
therapeutic efficacy
|
| gptkbp:isExpectedTo |
specific proteins
CRISPR/Cas9 siRNA plasmids expression vectors |
| gptkbp:isUsedFor |
clinical research
genetic engineering cell metabolism biochemical assays metabolic engineering gene expression studies protein characterization pharmacokinetics studies |
| gptkbp:isUtilizedFor |
cell signaling pathways
protein folding |
| gptkbp:isVisitedBy |
1960s
|
| gptkbp:knownFor |
producing therapeutic proteins
|
| gptkbp:mayHave |
gene expression
|
| gptkbp:suitableFor |
post-translational modifications
|
| gptkbp:usedIn |
biotechnology
|