Statements (19)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:genetic_disorder
|
| gptkbp:affects |
CCR5 gene
|
| gptkbp:associatedWith |
increased risk of West Nile virus infection
reduced risk of smallpox |
| gptkbp:discoveredIn |
1996
|
| gptkbp:frequency |
Northern European populations
|
| gptkbp:frequencyLowestIn |
gptkb:East_Asian_populations
gptkb:African_populations |
| gptkbp:heterozygousIndividuals |
partial resistance to HIV-1
|
| gptkbp:homozygousIndividuals |
high resistance to HIV-1
|
| gptkbp:lengthOfDeletion |
32 base pairs
|
| gptkbp:modeOfInheritance |
autosomal recessive
|
| gptkbp:resistantTo |
HIV-1 infection
|
| gptkbp:result |
truncated CCR5 protein
|
| gptkbp:usedIn |
gene editing research
HIV cure research |
| gptkbp:bfsParent |
gptkb:The_Berlin_Patient
|
| gptkbp:bfsLayer |
7
|
| https://www.w3.org/2000/01/rdf-schema#label |
CCR5-delta 32 mutation
|