Statements (20)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
immunotherapy
gene therapy |
| gptkbp:aimsTo |
induce immune tolerance
prevent transplant rejection treat autoimmune diseases |
| gptkbp:benefit |
reduce need for immunosuppression
|
| gptkbp:clinicalTrialPhase |
early phase
|
| gptkbp:developedBy |
autoimmune disorders
organ transplantation |
| gptkbp:firstDescribed |
2016
|
| https://www.w3.org/2000/01/rdf-schema#label |
CAR-Treg therapy
|
| gptkbp:mechanismOfAction |
engineered Tregs express CARs targeting specific antigens
|
| gptkbp:relatedTo |
gene therapy
|
| gptkbp:riskFactor |
off-target immunosuppression
|
| gptkbp:studiedBy |
academic institutions
biotechnology companies |
| gptkbp:uses |
gptkb:regulatory_T_cells
chimeric antigen receptor |
| gptkbp:bfsParent |
gptkb:TX200_(CAR-Treg_cell_therapy)
|
| gptkbp:bfsLayer |
7
|