Bowen's disease

GPTKB entity

Statements (32)
Predicate Object
gptkbp:instanceOf gptkb:disease
gptkb:skin
gptkbp:affects gptkb:skin
mucous membranes
gptkbp:alsoKnownAs squamous cell carcinoma in situ
gptkbp:canProgressTo invasive squamous cell carcinoma
gptkbp:commonIn elderly
fair-skinned individuals
gptkbp:diagnosedBy skin biopsy
gptkbp:firstDescribed 1912
John T. Bowen
gptkbp:histology full-thickness epidermal dysplasia
https://www.w3.org/2000/01/rdf-schema#label Bowen's disease
gptkbp:ICD-10_code D04
gptkbp:MeSH_ID D001932
gptkbp:notableFor intraepidermal carcinoma
gptkbp:OMIM 109600
gptkbp:predecessor invasive squamous cell carcinoma
gptkbp:prognosis good with treatment
gptkbp:riskFactor immunosuppression
human papillomavirus infection
arsenic exposure
chronic sun exposure
gptkbp:symptom red scaly patch
slowly enlarging lesion
well-demarcated plaque
gptkbp:treatment gptkb:photodynamic_therapy
cryotherapy
surgical excision
topical chemotherapy
gptkbp:bfsParent gptkb:cutaneous_squamous_cell_carcinoma
gptkbp:bfsLayer 6