Avonex

GPTKB entity

Properties (51)
Predicate Object
gptkbp:instanceOf medication
gptkbp:activeDuring interferon_beta-1a
gptkbp:administrativeDivision once a week
gptkbp:chemicalFormula protein
gptkbp:clinicalTrials Phase III
disease-modifying therapy
recommended_for_MS_treatment
gptkbp:community_service available
gptkbp:contraindication depression
liver enzyme elevation
hypersensitivity to interferon beta
thyroid dysfunction
gptkbp:date 1996-04-01
gptkbp:dosageForm solution
gptkbp:drugInterdiction available online
anticoagulants
antidepressants
other immunosuppressants
bioavailability 30%
gptkbp:endOfLife approximately 8 hours
gptkbp:formulation pre-filled syringe
gptkbp:gestationPeriod Category C
gptkbp:hasPopulation adults
gptkbp:healthcare liver function tests
complete blood count
thyroid function tests
important for adherence
https://www.w3.org/2000/01/rdf-schema#label Avonex
gptkbp:lastProduced gptkb:United_States
gptkbp:launchSite upper arm
thigh
buttock
gptkbp:mandates relapsing forms of multiple sclerosis
gptkbp:manufacturer gptkb:Biogen
gptkbp:marketedAs gptkb:Australia
gptkb:Canada
gptkb:European_Union
gptkbp:numberOfStudents renal
gptkbp:offers varies by region
gptkbp:researchInterest ongoing
gptkbp:route intramuscular injection
gptkbp:sells gptkb:Avonex
gptkbp:sideEffect fatigue
headache
muscle pain
injection site reactions
flu-like symptoms
gptkbp:storage refrigerated
gptkbp:triggerType immunomodulator
gptkbp:type interferon_beta-1a
gptkbp:usedFor multiple sclerosis