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gptkbp:instanceOf
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gptkb:cardiovascular_disease
Congenital heart defect
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gptkbp:abbreviation
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gptkb:ASD
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gptkbp:affectsOrgan
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gptkb:Heart
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gptkbp:affectsStructure
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Atrial septum
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gptkbp:canBeAsymptomatic
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True
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gptkbp:cause
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gptkb:Eisenmenger_syndrome
Right heart enlargement
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gptkbp:causedBy
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Abnormal development of the heart
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gptkbp:complication
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Stroke
Heart failure
Arrhythmia
Pulmonary hypertension
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gptkbp:diagnosedBy
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gptkb:Cardiac_MRI
gptkb:Chest_X-ray
Echocardiogram
Electrocardiogram
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gptkbp:firstDescribed
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1877
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gptkbp:hasEpidemiology
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More common in females
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gptkbp:hasType
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gptkb:Coronary_sinus_ASD
gptkb:Ostium_primum_ASD
gptkb:Ostium_secundum_ASD
gptkb:Sinus_venosus_ASD
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https://www.w3.org/2000/01/rdf-schema#label
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Atrial Septal Defect
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gptkbp:ICD-10_code
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Q21.1
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gptkbp:inheritance
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Autosomal dominant (rarely)
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gptkbp:MeSH_ID
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D001281
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gptkbp:OMIM
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607941
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gptkbp:prevalence
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1 in 1500 live births
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gptkbp:prognosis
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Good with treatment
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gptkbp:relatedTo
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gptkb:Patent_foramen_ovale
gptkb:Ventricular_septal_defect
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gptkbp:riskFactor
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Family history of congenital heart defects
Maternal alcohol use during pregnancy
Maternal diabetes
Maternal rubella infection during pregnancy
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gptkbp:symptom
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Fatigue
Shortness of breath
Heart murmur
Heart palpitations
Swelling of legs, feet, or abdomen
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gptkbp:treatment
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Observation
Catheter-based closure
Surgical repair
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gptkbp:bfsParent
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gptkb:ASD
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gptkbp:bfsLayer
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5
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