Statements (23)
| Predicate | Object | 
|---|---|
| gptkbp:instanceOf | 
                                    
                                        
                                            gptkb:immunosuppressant
                                        
                                         | 
                            
| gptkbp:activeIngredient | 
                                    
                                        
                                            gptkb:tacrolimus
                                        
                                         | 
                            
| gptkbp:approvedBy | 
                                    
                                        
                                            gptkb:FDA
                                        
                                         gptkb:EMA 2013  | 
                            
| gptkbp:ATCCode | 
                                    
                                        
                                            
                                            L04AD02
                                        
                                        
                                         | 
                            
| gptkbp:form | 
                                    
                                        
                                            
                                            extended-release capsule
                                        
                                        
                                         | 
                            
| gptkbp:legalStatus | 
                                    
                                        
                                            
                                            prescription only
                                        
                                        
                                         | 
                            
| gptkbp:manufacturer | 
                                    
                                        
                                            gptkb:Astellas_Pharma
                                        
                                         | 
                            
| gptkbp:mechanismOfAction | 
                                    
                                        
                                            gptkb:immunosuppressant
                                        
                                         | 
                            
| gptkbp:pregnancyCategory | 
                                    
                                        
                                            
                                            C (US)
                                        
                                        
                                         | 
                            
| gptkbp:routeOfAdministration | 
                                    
                                        
                                            
                                            oral
                                        
                                        
                                         | 
                            
| gptkbp:sideEffect | 
                                    
                                        
                                            
                                            hypertension
                                        
                                        
                                         tremor nephrotoxicity hyperglycemia increased risk of infection  | 
                            
| gptkbp:tradenameOf | 
                                    
                                        
                                            gptkb:tacrolimus_extended-release
                                        
                                         | 
                            
| gptkbp:usedFor | 
                                    
                                        
                                            
                                            kidney transplant
                                        
                                        
                                         prevention of organ rejection  | 
                            
| gptkbp:bfsParent | 
                                    
                                        
                                            gptkb:Prograf
                                        
                                         | 
                            
| gptkbp:bfsLayer | 
                                    
                                        
                                            
                                            6
                                        
                                        
                                         | 
                            
| https://www.w3.org/2000/01/rdf-schema#label | 
                                    
                                        
                                            
                                            Astagraf XL
                                        
                                        
                                         |