Properties (54)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
Medication
|
| gptkbp:activeDuring |
Trihexyphenidyl
|
| gptkbp:availability |
Generic_versions_available
|
| gptkbp:brand |
gptkb:Artane
Trihexane |
| gptkbp:chemicalFormula |
C19H26N2O
|
| gptkbp:clinicalTrials |
Conducted for efficacy
Conducted for safety |
| gptkbp:contraindication |
gptkb:Myasthenia_gravis
Glaucoma Prostatic hypertrophy |
| gptkbp:drugInterdiction |
Consult healthcare provider
Rapid absorption Anticholinergic effects Anticholinergic_agent |
| gptkbp:emergencyServices |
Activated charcoal
Supportive care |
| gptkbp:endOfLife |
3 to 6 hours
|
| gptkbp:firstAppearance |
1950s
|
| gptkbp:formulation |
Liquid
Tablet |
| gptkbp:healthcare |
Regular follow-ups
Avoid driving until effects known Inform about side effects Stay hydrated to reduce dry mouth |
| https://www.w3.org/2000/01/rdf-schema#label |
Artane
|
| gptkbp:impact |
As prescribed by a physician
|
| gptkbp:interactsWith |
Antihistamines
Alcohol Other anticholinergics |
| gptkbp:isATypeOf |
15899-75-5
|
| gptkbp:legalStatus |
Prescription only
|
| gptkbp:manufacturer |
Various
|
| gptkbp:marketedAs |
gptkb:Canada
gptkb:United_Kingdom gptkb:United_States |
| gptkbp:operates_in |
N04AA02
|
| gptkbp:researchInterest |
Ongoing for combination therapies
Ongoing for new formulations |
| gptkbp:route |
Oral
|
| gptkbp:sideEffect |
Dizziness
Nausea Constipation Blurred vision Dry mouth |
| gptkbp:storage |
Room temperature
|
| gptkbp:symptoms |
Confusion
Hallucinations Severe_dizziness |
| gptkbp:usedFor |
Parkinson's disease
Extrapyramidal_symptoms |
| gptkbp:waterManagement |
Renal
|
| gptkbp:weight |
282.42 g/mol
|
| gptkbp:yearEstablished |
Gradual tapering recommended
|