Statements (27)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:chemical_compound
|
| gptkbp:application |
pharmaceutical synthesis
synthesis of complex molecules |
| gptkbp:canBe |
acid-catalyzed
base-catalyzed |
| gptkbp:cause |
aldol condensation
|
| gptkbp:commonCatalyst |
gptkb:carboxylic_acid
hydroxide ion |
| gptkbp:commonReagents |
aldehydes
ketones |
| gptkbp:field |
organic chemistry
|
| gptkbp:firstReported |
gptkb:Charles-Adolphe_Wurtz
1872 |
| https://www.w3.org/2000/01/rdf-schema#label |
Aldol reaction
|
| gptkbp:importantFor |
key reaction in organic synthesis
|
| gptkbp:involves |
carbonyl compound
enolate ion |
| gptkbp:mechanismOfAction |
nucleophilic addition
|
| gptkbp:namedAfter |
aldol (aldehyde + alcohol)
|
| gptkbp:product |
β-hydroxy carbonyl compound
α,β-unsaturated carbonyl compound (after dehydration) |
| gptkbp:type |
carbon–carbon bond-forming reaction
|
| gptkbp:variant |
crossed aldol reaction
intramolecular aldol reaction retro-aldol reaction |
| gptkbp:bfsParent |
gptkb:Organic_Chemistry
|
| gptkbp:bfsLayer |
6
|