Albendazole

GPTKB entity

Statements (52)
Predicate Object
gptkbp:instanceOf anthelmintic drug
gptkbp:affiliatedWith benzimidazole
gptkbp:approvalYear 1996
gptkbp:approvedBy gptkb:FDA
gptkbp:ATCCode P02CA03
gptkbp:brand gptkb:Zentel
gptkb:Albenza
gptkb:Andazol
gptkb:Eskazole
gptkb:Valbazen
gptkbp:CASNumber 54965-21-8
gptkbp:chemicalFormula C12H15N3O2S
gptkbp:contraindication pregnancy
known hypersensitivity
gptkbp:developedBy 1975
gptkbp:discoveredBy GlaxoSmithKline
gptkbp:eliminationHalfLife 8.5 hours
gptkbp:excretion urine
bile
https://www.w3.org/2000/01/rdf-schema#label Albendazole
gptkbp:includedIn gptkb:WHO_Model_List_of_Essential_Medicines
gptkbp:legalStatus prescription only
gptkbp:mechanismOfAction binds to beta-tubulin
inhibits microtubule polymerization
gptkbp:metabolism liver
gptkbp:molecularWeight 265.33 g/mol
gptkbp:pregnancyCategory C (US)
gptkbp:PubChem_CID 2082
DB00518
gptkbp:routeOfAdministration oral
gptkbp:sideEffect nausea
vomiting
abdominal pain
dizziness
headache
hair loss
elevated liver enzymes
bone marrow suppression
gptkbp:UNII F4216019LN
gptkbp:usedFor treatment of strongyloidiasis
treatment of ascariasis
treatment of cutaneous larva migrans
treatment of filariasis
treatment of giardiasis
treatment of hookworm infection
treatment of hydatid disease
treatment of neurocysticercosis
treatment of parasitic worm infestations
treatment of trichuriasis
treatment of enterobiasis
gptkbp:bfsParent gptkb:Tapeworm
gptkbp:bfsLayer 6