Abraxane for Injectable Suspension
GPTKB entity
Properties (54)
Predicate | Object |
---|---|
gptkbp:instanceOf |
chemotherapy drug
|
gptkbp:activeDuring |
paclitaxel
|
gptkbp:chemicalFormula |
C47H51NO14
|
gptkbp:clinicalTrials |
oncology
Phase III ABRAXANE trial MPC-350-001_trial MPC-350-002_trial MPC-350-003_trial MPC-350-004_trial |
gptkbp:contraindication |
anemia
allergic reactions vomiting diarrhea constipation infection thrombocytopenia severe liver impairment hypersensitivity to paclitaxel stomatitis |
gptkbp:date |
FDA_approved
|
gptkbp:distribution |
approximately 1000 L
|
gptkbp:dosageForm |
suspension
|
gptkbp:drugInterdiction |
antineoplastic agent
protein-bound |
gptkbp:firstAppearance |
2005
|
gptkbp:formulation |
injectable suspension
|
gptkbp:hasVariants |
with carboplatin
with gemcitabine |
https://www.w3.org/2000/01/rdf-schema#label |
Abraxane for Injectable Suspension
|
gptkbp:isATypeOf |
97058-78-3
|
gptkbp:mandates |
metastatic breast cancer
metastatic non-small cell lung cancer metastatic pancreatic cancer |
gptkbp:manufacturer |
gptkb:Celgene_Corporation
|
gptkbp:numberOfStudents |
13 hours
|
gptkbp:nutritionalValue |
liver
|
gptkbp:operates_in |
L01CD01
|
gptkbp:packaging |
vial
|
gptkbp:route |
intravenous
IV infusion |
gptkbp:sells |
gptkb:Abraxane
|
gptkbp:shelfLife |
24 months
|
gptkbp:sideEffect |
fatigue
nausea peripheral neuropathy hair loss neutropenia |
gptkbp:storage |
refrigerated
|
gptkbp:triggerType |
microtubule inhibitor
|
gptkbp:usedFor |
treatment of pancreatic cancer
treatment of breast cancer treatment of non-small cell lung cancer |
gptkbp:waterManagement |
bile
|