Triple

T5114789
Position Surface form Disambiguated ID Type / Status
Subject APOE ε4 allele E115305 entity
Predicate encodes P14248 FINISHED
Object apolipoprotein E4 isoform
The apolipoprotein E4 isoform is a variant of the ApoE protein strongly associated with increased risk of late-onset Alzheimer’s disease and cardiovascular disorders.
 E115305 NE FINISHED

How this triple was built (4 steps)

Every LLM step that produced this triple, in pipeline order — named-entity classification, the disambiguation choices (the exact options shown, with the pick highlighted), and the generated description. The batch + timestamp of each is in the Provenance table below.

NER Named-entity recognition gpt-5-mini
Instruction
Given a phrase, classify it is english named entity (e.g., persons, organizations, works of art) in Latin script, or not (e.g., literals, dates, URLs, verbose phrases). For disambiguation, the statement where the phrase occurs as object is also given. Please return a JSON object with `phrase` (string, the phrase being analyzed) and `is_ne` (boolean, indicating whether the phrase is a Named Entity).
Input
Phrase: apolipoprotein E4 isoform | Statement: [APOE ε4 allele, encodes, apolipoprotein E4 isoform]
NED1 Entity disambiguation (via context triple) gpt-5-mini-2025-08-07 
Target entity: apolipoprotein E4 isoform
Context triple: [APOE ε4 allele, encodes, apolipoprotein E4 isoform]
  • A. APOE ε4 allele
    The APOE ε4 allele is a genetic variant of the apolipoprotein E gene that significantly increases an individual's susceptibility to late-onset Alzheimer's disease.
  • B. E4
    E4 is a major European route and highway running through Sweden, forming a key north–south transport corridor.
  • C. E4
    E4 is a British digital television channel from Channel 4, known for airing popular entertainment, comedy, and drama series aimed primarily at younger audiences.
  • D. Alzon
    The Alzon is a river in southern France that flows through the Gard department, including the town of Uzès.
  • E. C9orf72
    C9orf72 is a human gene whose hexanucleotide repeat expansions are the most common known genetic cause of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD).
  • F. None of above. chosen
  • G. Unsure - the case is ambiguous/there is not enough information to decide.
NEDg Description generation gpt-5.1
Instruction
Generate a one-sentence description of the target entity. 
You are given a context triple in the form (subject, predicate, object), where the object is the target entity. 
# Instructions
Use the triple to infer relevant information about the entity. Describe the entity based on what is most defining, well-known. 
Avoid repeating the information from the triple, unless really essential.
# Response Format
Return only the sentence: "Description: [one-sentence description of the target entity]"
Input
Entity: apolipoprotein E4 isoform
Triple: [APOE ε4 allele, encodes, apolipoprotein E4 isoform]
Generated description
The apolipoprotein E4 isoform is a variant of the ApoE protein strongly associated with increased risk of late-onset Alzheimer’s disease and cardiovascular disorders.
NED2 Entity disambiguation (via description) gpt-5-mini-2025-08-07 
Target entity: apolipoprotein E4 isoform
Target entity description: The apolipoprotein E4 isoform is a variant of the ApoE protein strongly associated with increased risk of late-onset Alzheimer’s disease and cardiovascular disorders.
  • A. APOE ε4 allele chosen
    The APOE ε4 allele is a genetic variant of the apolipoprotein E gene that significantly increases an individual's susceptibility to late-onset Alzheimer's disease.
  • B. E4
    E4 is a major European route and highway running through Sweden, forming a key north–south transport corridor.
  • C. E4
    E4 is a British digital television channel from Channel 4, known for airing popular entertainment, comedy, and drama series aimed primarily at younger audiences.
  • D. Alzon
    The Alzon is a river in southern France that flows through the Gard department, including the town of Uzès.
  • E. C9orf72
    C9orf72 is a human gene whose hexanucleotide repeat expansions are the most common known genetic cause of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD).
  • F. None of above.

Provenance (5 batches)

The batch behind each pipeline step, in order, with when it ran. Timestamps are batch-level — stages were processed in waves, so the object chain (NER → NED1 → NEDg → NED2) reads in order, but predicate / elicitation batches can sit in a different wave.

Step Stage Batch ID Status When
creating Elicitation batch_69bd4441d1648190a54a533895041987 completed March 20, 2026, 12:57 p.m.
NER Named-entity recognition batch_69bd75cd13a08190b53e67ba65333557 completed March 20, 2026, 4:29 p.m.
NED1 Entity disambiguation (via context triple) batch_69bebaadfaac8190aa0407196e5c4c20 completed March 21, 2026, 3:35 p.m.
NEDg Description generation batch_69bebb1a4370819085bcbe73a0b8c68e completed March 21, 2026, 3:36 p.m.
NED2 Entity disambiguation (via description) batch_69bebcf63784819097be14bb7dcbf4d9 completed March 21, 2026, 3:44 p.m.
Created at: March 20, 2026, 1:41 p.m.