Triple
T31544656
| Position | Surface form | Disambiguated ID | Type / Status |
|---|---|---|---|
| Subject | carbidopa |
E804842
|
entity |
| Predicate | instanceOf |
P0
|
FINISHED |
| Object | decarboxylase inhibitor |
C58354
|
CONCEPT FINISHED |
How this triple was built (1 step)
Every LLM step that produced this triple, in pipeline order — named-entity classification, the disambiguation choices (the exact options shown, with the pick highlighted), and the generated description. The batch + timestamp of each is in the Provenance table below.
CD
Concept disambiguation
gpt-5-mini-2025-08-07
Target class: decarboxylase inhibitor Context triple: [carbidopa, instanceOf, decarboxylase inhibitor]
-
A.
decarboxylase
A decarboxylase is an enzyme that catalyzes the removal of a carboxyl group from organic molecules, releasing carbon dioxide.
-
B.
aromatic L-amino acid decarboxylase inhibitor
chosen
An aromatic L-amino acid decarboxylase inhibitor is a drug that blocks the enzyme responsible for converting aromatic L-amino acids (like levodopa) into their corresponding neurotransmitters, thereby increasing the availability of these precursors for therapeutic use, particularly in Parkinson’s disease.
-
C.
catechol-O-methyltransferase inhibitor
A catechol-O-methyltransferase inhibitor is a drug that blocks the COMT enzyme to prevent the breakdown of catecholamines (such as dopamine), thereby prolonging and enhancing their effects, often used as an adjunct therapy in Parkinson’s disease.
-
D.
BCRP inhibitor
A BCRP inhibitor is a compound that reduces or blocks the activity of the Breast Cancer Resistance Protein (ABCG2) efflux transporter, thereby altering the absorption, distribution, and elimination of its substrate drugs.
-
E.
glutamate release inhibitor
A glutamate release inhibitor is an agent that reduces the presynaptic release of the excitatory neurotransmitter glutamate, thereby modulating neuronal excitability and protecting against excitotoxicity.
- F. None of above.
Provenance (1 batch)
The batch behind each pipeline step, in order, with when it ran. Timestamps are batch-level — stages were processed in waves, so the object chain (NER → NED1 → NEDg → NED2) reads in order, but predicate / elicitation batches can sit in a different wave.
| Step | Stage | Batch ID | Status | When |
|---|---|---|---|---|
| creating | Elicitation | batch_69f348d11a048190a65eb8384a3754ac |
completed | April 30, 2026, 12:19 p.m. |
Created at: April 30, 2026, 10:07 p.m.