Triple

T22889013
Position Surface form Disambiguated ID Type / Status
Subject CYP2C19 E567681 entity
Predicate metabolizes P37221 FINISHED
Object mephenytoin
Mephenytoin is an anticonvulsant drug historically used to treat epilepsy and known for its role as a probe substrate in pharmacogenetic studies of CYP2C19 enzyme activity.
 E1559896 NE FINISHED

How this triple was built (4 steps)

Every LLM step that produced this triple, in pipeline order — named-entity classification, the disambiguation choices (the exact options shown, with the pick highlighted), and the generated description. The batch + timestamp of each is in the Provenance table below.

NER Named-entity recognition gpt-5-mini
Instruction
Given a phrase, classify it is english named entity (e.g., persons, organizations, works of art) in Latin script, or not (e.g., literals, dates, URLs, verbose phrases). For disambiguation, the statement where the phrase occurs as object is also given. Please return a JSON object with `phrase` (string, the phrase being analyzed) and `is_ne` (boolean, indicating whether the phrase is a Named Entity).
Input
Phrase: mephenytoin | Statement: [CYP2C19, metabolizes, mephenytoin]
NED1 Entity disambiguation (via context triple) gpt-5-mini-2025-08-07 
Target entity: mephenytoin
Context triple: [CYP2C19, metabolizes, mephenytoin]
  • A. phenytoin
    Phenytoin is an antiepileptic medication commonly used to prevent and control seizures by stabilizing neuronal activity in the brain.
  • B. carbamazepine
    Carbamazepine is an anticonvulsant and mood-stabilizing drug commonly used to treat epilepsy, trigeminal neuralgia, and bipolar disorder.
  • C. valproate
    Valproate is an anticonvulsant and mood-stabilizing medication widely used to treat epilepsy, bipolar disorder, and to prevent migraine headaches.
  • D. lamotrigine
    Lamotrigine is an anticonvulsant medication primarily used to treat epilepsy and bipolar disorder by stabilizing neuronal activity and reducing the frequency of seizures or mood episodes.
  • E. vigabatrin
    Vigabatrin is an antiepileptic medication that irreversibly inhibits GABA transaminase to increase brain GABA levels, used mainly for refractory seizures such as infantile spasms but associated with risks like permanent visual field loss.
  • F. None of above. chosen
  • G. Unsure - the case is ambiguous/there is not enough information to decide.
NEDg Description generation gpt-5.1
Instruction
Generate a one-sentence description of the target entity. 
You are given a context triple in the form (subject, predicate, object), where the object is the target entity. 
# Instructions
Use the triple to infer relevant information about the entity. Describe the entity based on what is most defining, well-known. 
Avoid repeating the information from the triple, unless really essential.
# Response Format
Return only the sentence: "Description: [one-sentence description of the target entity]"
Input
Entity: mephenytoin
Triple: [CYP2C19, metabolizes, mephenytoin]
Generated description
Mephenytoin is an anticonvulsant drug historically used to treat epilepsy and known for its role as a probe substrate in pharmacogenetic studies of CYP2C19 enzyme activity.
NED2 Entity disambiguation (via description) gpt-5-mini-2025-08-07 
Target entity: mephenytoin
Target entity description: Mephenytoin is an anticonvulsant drug historically used to treat epilepsy and known for its role as a probe substrate in pharmacogenetic studies of CYP2C19 enzyme activity.
  • A. phenytoin
    Phenytoin is an antiepileptic medication commonly used to prevent and control seizures by stabilizing neuronal activity in the brain.
  • B. carbamazepine
    Carbamazepine is an anticonvulsant and mood-stabilizing drug commonly used to treat epilepsy, trigeminal neuralgia, and bipolar disorder.
  • C. valproate
    Valproate is an anticonvulsant and mood-stabilizing medication widely used to treat epilepsy, bipolar disorder, and to prevent migraine headaches.
  • D. lamotrigine
    Lamotrigine is an anticonvulsant medication primarily used to treat epilepsy and bipolar disorder by stabilizing neuronal activity and reducing the frequency of seizures or mood episodes.
  • E. vigabatrin
    Vigabatrin is an antiepileptic medication that irreversibly inhibits GABA transaminase to increase brain GABA levels, used mainly for refractory seizures such as infantile spasms but associated with risks like permanent visual field loss.
  • F. None of above. chosen

Provenance (5 batches)

The batch behind each pipeline step, in order, with when it ran. Timestamps are batch-level — stages were processed in waves, so the object chain (NER → NED1 → NEDg → NED2) reads in order, but predicate / elicitation batches can sit in a different wave.

Step Stage Batch ID Status When
creating Elicitation batch_69e2458a92ec81908fc1cd5f6407d2ab completed April 17, 2026, 2:36 p.m.
NER Named-entity recognition batch_69f17fc37a448190996e106aacc900f4 completed April 29, 2026, 3:49 a.m.
NED1 Entity disambiguation (via context triple) batch_6a0bb9c03a2481909a2c41b6cdab0363 completed May 19, 2026, 1:15 a.m.
NEDg Description generation batch_6a0bbb6ca76c8190bde7e1eacb121d23 completed May 19, 2026, 1:22 a.m.
NED2 Entity disambiguation (via description) batch_6a0bbc1bd0808190a0a5f8f603308b45 completed May 19, 2026, 1:25 a.m.
Created at: April 17, 2026, 3:40 p.m.