Statements (54)
| Predicate | Object |
|---|---|
| gptkbp:instance_of |
gptkb:chemical_compound
|
| gptkbp:bfsLayer |
5
|
| gptkbp:bfsParent |
gptkb:carbamazepine
|
| gptkbp:activities |
increases GABA levels
|
| gptkbp:approves |
gptkb:FDA
|
| gptkbp:associated_with |
polycystic ovary syndrome
neural tube defects |
| gptkbp:brand |
Depakote
Epival Depakene |
| gptkbp:category |
gptkb:D
|
| gptkbp:class |
gptkb:drug
mood stabilizer |
| gptkbp:contraindication |
liver disease
urea cycle disorders |
| gptkbp:discovered_by |
1960s
|
| gptkbp:dosage_form |
10-60 mg/kg/day
|
| gptkbp:duration |
varies by condition
|
| gptkbp:excretion |
urine
feces |
| https://www.w3.org/2000/01/rdf-schema#label |
valproate
|
| gptkbp:ingredients |
C8 H16 N2 O2
|
| gptkbp:interacts_with |
gptkb:phenobarbital
gptkb:lamotrigine gptkb:carbamazepine gptkb:warfarin aspirin |
| gptkbp:is_atype_of |
N03 A G01
|
| gptkbp:is_available_on |
oral tablet
oral solution injectable form |
| gptkbp:is_monitored_by |
liver function tests
blood levels |
| gptkbp:is_used_for |
treating epilepsy
treating bipolar disorder preventing migraine headaches |
| gptkbp:lifespan |
9 to 16 hours
|
| gptkbp:metabolism |
liver
|
| gptkbp:side_effect |
nausea
liver damage weight gain hair loss tremor |
| gptkbp:suitable_for |
pregnant women
breastfeeding women children under 2 years |
| gptkbp:symptoms |
confusion
drowsiness respiratory depression coma |
| gptkbp:treatment |
gptkb:psychologist
bipolar disorder migraine prophylaxis |
| gptkbp:type_of |
99-66-1
|