gptkbp:instance_of
|
gptkb:chemical_compound
|
gptkbp:approves
|
gptkb:FDA
|
gptkbp:associated_with
|
polycystic ovary syndrome
neural tube defects
|
gptkbp:atccode
|
N03 AG01
|
gptkbp:available_on
|
oral tablet
oral solution
injectable form
|
gptkbp:brand
|
Depakote
Epival
Depakene
|
gptkbp:casnumber
|
99-66-1
|
gptkbp:category
|
gptkb:D
|
gptkbp:chemical_formula
|
C8 H16 N2 O2
|
gptkbp:class
|
gptkb:Antihero
mood stabilizer
|
gptkbp:contraindication
|
liver disease
urea cycle disorders
|
gptkbp:discovered_by
|
1960s
|
gptkbp:dosage_form
|
10-60 mg/kg/day
|
gptkbp:drug_interactions
|
gptkb:phenobarbital
gptkb:lamotrigine
gptkb:carbamazepine
gptkb:warfarin
aspirin
|
gptkbp:duration
|
varies by condition
|
gptkbp:excretion
|
urine
feces
|
https://www.w3.org/2000/01/rdf-schema#label
|
valproate
|
gptkbp:is_monitored_by
|
liver function tests
blood levels
|
gptkbp:lifespan
|
9 to 16 hours
|
gptkbp:mechanism_of_action
|
increases GABA levels
|
gptkbp:metabolism
|
liver
|
gptkbp:side_effect
|
nausea
liver damage
weight gain
hair loss
tremor
|
gptkbp:suitable_for
|
pregnant women
breastfeeding women
children under 2 years
|
gptkbp:symptoms
|
confusion
drowsiness
respiratory depression
coma
|
gptkbp:treatment
|
gptkb:epilepsy
bipolar disorder
migraine prophylaxis
|
gptkbp:used_for
|
treating epilepsy
treating bipolar disorder
preventing migraine headaches
|
gptkbp:bfsParent
|
gptkb:carbamazepine
|
gptkbp:bfsLayer
|
5
|