unicentric Castleman disease
GPTKB entity
Statements (63)
| Predicate | Object |
|---|---|
| gptkbp:instance_of |
gptkb:castle
|
| gptkbp:affects |
lymph nodes
|
| gptkbp:can_be_asymptomatic_in |
some patients
|
| gptkbp:can_be_differentiated_from |
gptkb:sarcoidosis
|
| gptkbp:can_be_used_to |
gptkb:anemia
fatigue weight loss fever night sweats |
| gptkbp:can_cause |
compression of surrounding structures
|
| gptkbp:can_involve |
excision of the affected lymph node
|
| gptkbp:can_lead_to |
gptkb:Oncology
|
| gptkbp:caused_by |
bacterial infections
|
| gptkbp:complications |
gptkb:disease
|
| gptkbp:condition |
can affect quality of life
affects the immune system can be life-threatening in rare cases |
| gptkbp:diagnosis |
clinical evaluation
biopsy immunohistochemistry |
| https://www.w3.org/2000/01/rdf-schema#label |
unicentric Castleman disease
|
| gptkbp:is_a_rare_form_of |
lymphadenopathy
|
| gptkbp:is_associated_with |
autoimmune diseases
chronic inflammation HIV infection human herpesvirus 8 (HHV-8) systemic symptoms elevated inflammatory markers lymphatic dysfunction |
| gptkbp:is_characterized_by |
vascular proliferation
hyperplastic lymphoid tissue localized lymphadenopathy plasma cell proliferation single enlarged lymph node |
| gptkbp:is_common_in |
young adults
|
| gptkbp:is_described_as |
gptkb:malignant_lymphomas
|
| gptkbp:is_different_from |
gptkb:multicentric_Castleman_disease
|
| gptkbp:is_evaluated_by |
hematologists
|
| gptkbp:is_linked_to |
genetic factors
|
| gptkbp:is_managed_by |
specialists in hematology
|
| gptkbp:is_monitored_by |
imaging studies
|
| gptkbp:is_often_associated_with |
thrombocytopenia
|
| gptkbp:is_often_described_as |
gptkb:localized_Castleman_disease
|
| gptkbp:is_often_researched_in |
clinical trials
|
| gptkbp:is_often_seen_in |
other lymphoproliferative disorders
|
| gptkbp:is_part_of_a_group_of_diseases_known_as |
lymphoproliferative disorders
|
| gptkbp:may_require_follow-up_for |
recurrence
|
| gptkbp:occurs_in |
any age group
|
| gptkbp:rarity |
in the general population
|
| gptkbp:requires |
gptkb:immunotherapy
palliative care radiation therapy long-term follow-up multidisciplinary management |
| gptkbp:scientific_classification |
benign
|
| gptkbp:treatment |
gptkb:surgery
targeted therapies oncologists corticosteroids antiviral medications |
| gptkbp:type_of |
gptkb:castle
|
| gptkbp:bfsParent |
gptkb:castle
|
| gptkbp:bfsLayer |
4
|