Statements (59)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
bone cells
|
| gptkbp:are |
cuboidal in shape
|
| gptkbp:can_be |
mechanical loading
growth hormone collagen type I become osteocytes proteins involved in mineralization |
| gptkbp:community |
RANKL
|
| gptkbp:createdBy |
bone matrix
osteocalcin |
| gptkbp:diedIn |
bone healing
|
| gptkbp:enables |
glucocorticoids
certain medications |
| gptkbp:function |
bone_formation
|
| gptkbp:has |
cellular receptors
|
| https://www.w3.org/2000/01/rdf-schema#label |
osteoblasts
|
| gptkbp:impact |
gptkb:parathyroid_hormone
Wnt signaling pathway age-related changes |
| gptkbp:influence |
bone remodeling
|
| gptkbp:influenced |
estrogen
vitamin D insulin-like growth factor |
| gptkbp:interactsWith |
osteoclasts
|
| gptkbp:introduced |
alkaline phosphatase
|
| gptkbp:involvedIn |
calcium homeostasis
|
| gptkbp:is_a_source_of |
the embryonic mesoderm
the mesoderm |
| gptkbp:is_available_in |
bone marrow
periosteum |
| gptkbp:is_characterized_by |
high alkaline phosphatase activity
|
| gptkbp:is_essential_for |
bone mineralization
bone density maintenance bone growth fracture repair maintaining bone strength the development of the skeletal system |
| gptkbp:is_governed_by |
cytokines
mechanical stress |
| gptkbp:is_involved_in |
osteogenesis
bone remodeling cycle the maintenance of bone mass the regulation of calcium levels the repair of bone fractures the response to mechanical stress the synthesis of bone matrix proteins |
| gptkbp:is_part_of |
the skeletal system
|
| gptkbp:is_promoted_through |
gptkb:calcitonin
|
| gptkbp:locatedIn |
bone tissue
|
| gptkbp:origin |
mesenchymal stem cells
|
| gptkbp:originatesFrom |
osteoprogenitor cells
|
| gptkbp:produces |
osteoid
|
| gptkbp:provides |
bone sialoprotein
|
| gptkbp:regulates |
mineralization
|
| gptkbp:released |
growth factors
|
| gptkbp:respondsTo |
hormones
|
| gptkbp:safetyFeatures |
other bone cells
|
| gptkbp:variant |
osteocytes
|
| gptkbp:winner |
apoptosis
|