Statements (63)
| Predicate | Object |
|---|---|
| gptkbp:instance_of |
gptkb:disease
|
| gptkbp:affects |
gptkb:children
|
| gptkbp:associated_with |
gptkb:Beckwith-Wiedemann_syndrome
gptkb:WAGR_syndrome |
| gptkbp:cause |
abdominal mass
|
| gptkbp:clinical_trial |
gptkb:anemia
hypertension metastasis to liver metastasis to lungs available for new therapies large abdominal mass metastasis to lymph nodes |
| gptkbp:death |
around 70% for metastatic cases
over 90% for localized cases |
| gptkbp:diagnosis |
gptkb:MRI
gptkb:alpha-fetoprotein CT scan ultrasound urinary catecholamines good if detected early |
| gptkbp:diseases |
gptkb:embryonal_tumor
blastemal component epithelial component stromal component triphasic histology |
| gptkbp:events |
monitoring for recurrence
long-term health assessments regular imaging |
| gptkbp:first_described_by |
gptkb:Max_Wilms
|
| gptkbp:genetic_studies |
chromosomal abnormalities
|
| https://www.w3.org/2000/01/rdf-schema#label |
nephroblastoma
|
| gptkbp:known_as |
gptkb:Wilms_tumor
|
| gptkbp:number_of_stages |
staged I to V
|
| gptkbp:occurs_in |
most common kidney cancer in children
|
| gptkbp:premiered_on |
typically diagnosed between ages 3 and 4
|
| gptkbp:provides_guidance_on |
gptkb:European_Society_for_Medical_Oncology
gptkb:National_Comprehensive_Cancer_Network gptkb:Children's_Oncology_Group |
| gptkbp:research |
ongoing for better treatments
|
| gptkbp:research_focus |
gptkb:immunotherapy
genetic predisposition targeted therapy biomarkers for prognosis |
| gptkbp:risk_factor |
family history
congenital anomalies |
| gptkbp:symptoms |
nausea
weight loss fever hematuria pain in the abdomen swelling in the abdomen |
| gptkbp:treatment |
gptkb:surgery
palliative care radiation therapy chemotherapy clinical management adjuvant therapy depends on stage at diagnosis nephrectomy neoadjuvant chemotherapy postoperative chemotherapy |
| gptkbp:bfsParent |
gptkb:Wilms_tumor
|
| gptkbp:bfsLayer |
7
|