Statements (57)
| Predicate | Object |
|---|---|
| gptkbp:instance_of |
gptkb:CAR_T-cell_therapy
|
| gptkbp:are_generated |
after initial infection or vaccination
|
| gptkbp:are_part_of |
adaptive immune system
|
| gptkbp:can_be |
activated by cytokines
|
| gptkbp:can_be_expanded_in |
in vitro cultures
|
| gptkbp:can_be_found_in |
peripheral blood
|
| gptkbp:can_be_generated_in_response_to |
various pathogens
|
| gptkbp:can_create |
through vaccination strategies
surface markers like CD44 |
| gptkbp:can_provide |
in the formation of memory B cells
|
| gptkbp:can_provide_help_to |
cytotoxic T cells
|
| gptkbp:contribution |
vaccine efficacy
|
| gptkbp:development |
from central memory T cells
from effector memory T cells |
| gptkbp:differentiate |
into effector T cells upon re-exposure to antigen
|
| gptkbp:evaluates |
flow cytometry
|
| gptkbp:exhibits |
plasticity in their function
|
| gptkbp:function |
enhance the immune response
help activate B cells |
| gptkbp:has_produced |
stem cells in the bone marrow
|
| gptkbp:has_role |
autoimmunity
|
| https://www.w3.org/2000/01/rdf-schema#label |
memory T-helper cells
|
| gptkbp:influence |
B cell differentiation
the differentiation of other immune cells |
| gptkbp:initiated_by |
requires antigen presentation
|
| gptkbp:interacts_with |
with antigen-presenting cells
|
| gptkbp:involved_in |
secondary immune response
|
| gptkbp:is_affected_by |
chronic stress
age and health status |
| gptkbp:is_characterized_by |
their ability to persist in the body
their cytokine production profile |
| gptkbp:is_essential_for |
controlling chronic infections
effective immune memory long-term protection against pathogens |
| gptkbp:is_influenced_by |
hormonal changes
microenvironmental factors |
| gptkbp:is_involved_in |
transplant rejection
tumor immunity allergic responses vaccine-induced immunity the regulation of immune responses |
| gptkbp:is_recognized_by |
specific markers
|
| gptkbp:is_studied_in |
immunology research
clinical trials. |
| gptkbp:is_targeted_at |
immunotherapies
|
| gptkbp:location |
lymph nodes
|
| gptkbp:migration |
to sites of infection
|
| gptkbp:occurs_in |
clonal expansion upon reactivation
|
| gptkbp:origin |
develop from naive T cells
|
| gptkbp:produces |
cytokines
|
| gptkbp:recognizes |
specific antigens
|
| gptkbp:response_time |
faster than naive T cells
|
| gptkbp:role |
provide long-term immunity
|
| gptkbp:survivors |
long-lived in the body
|
| gptkbp:type_of |
gptkb:CD4+_T_cells
|
| gptkbp:bfsParent |
gptkb:T-helper_17_cells
|
| gptkbp:bfsLayer |
7
|