Statements (60)
| Predicate | Object |
|---|---|
| gptkbp:instance_of |
gptkb:protein
|
| gptkbp:bfsLayer |
5
|
| gptkbp:bfsParent |
gptkb:AKT
|
| gptkbp:associated_with |
gptkb:healthcare_organization
gptkb:Company obesity |
| gptkbp:discovered_by |
gptkb:David_Sabatini
|
| gptkbp:established |
gptkb:Company
gptkb:everolimus stress amino acids growth factors hypoxia autophagy rapamycin temsirolimus nutrient deprivation |
| gptkbp:function |
regulates cell growth
regulates autophagy regulates cell proliferation regulates cell survival regulates protein synthesis |
| https://www.w3.org/2000/01/rdf-schema#label |
m TOR
|
| gptkbp:is_a_route_for |
m TOR C1
m TOR C2 |
| gptkbp:is_found_in |
eukaryotic cells
|
| gptkbp:is_involved_in |
DNA repair
aging cell cycle regulation metabolic disorders chronic diseases inflammation metabolic syndrome neuroplasticity stress response fibrosis cardiovascular diseases cellular differentiation immune cell activation neurodegeneration muscle hypertrophy stem cell maintenance cellular signaling nutrient sensing |
| gptkbp:location |
gptkb:physicist
cytoplasm |
| gptkbp:regulates |
metabolism
cellular homeostasis glycolysis immune response mitochondrial function angiogenesis ribosome biogenesis lipid synthesis |
| gptkbp:targets |
gptkb:AKT
4 EB P1 HIF-1α S6 K1 UL K1 |
| gptkbp:year_created |
gptkb:1994
|