Statements (67)
| Predicate | Object |
|---|---|
| gptkbp:instance_of |
gptkb:healthcare_organization
|
| gptkbp:advocates_for |
gptkb:Retinoblastoma_International
|
| gptkbp:affects |
gptkb:Person
|
| gptkbp:age |
infancy
|
| gptkbp:associated_with |
gptkb:pineoblastoma
gptkb:neuroblastoma other cancers |
| gptkbp:caused_by |
R B1 gene mutation
|
| gptkbp:clinical_trial |
ongoing research
visual impairment retinal detachment leukocoria tumor calcification unilateral or bilateral |
| gptkbp:descendant |
autosomal dominant
|
| gptkbp:end_of_life |
high with treatment
|
| gptkbp:events |
long-term monitoring
|
| gptkbp:first_described_by |
1930s
|
| gptkbp:genetic_diversity |
deletion
point mutation recommended for families |
| https://www.w3.org/2000/01/rdf-schema#label |
hereditary retinoblastoma
|
| gptkbp:is_involved_in |
local organizations
online communities parent support networks |
| gptkbp:is_popular_in |
rare
|
| gptkbp:promoter |
R B1
|
| gptkbp:public_awareness |
gptkb:Educational_Institution
gptkb:charity advocacy initiatives retinoblastoma awareness month |
| gptkbp:research_focus |
gptkb:physicist
gptkb:vaccine targeted therapy |
| gptkbp:risk_factor |
gptkb:bilateral_retinoblastoma
family history exposure to radiation advanced maternal age certain genetic syndromes |
| gptkbp:screenings |
regular eye exams
|
| gptkbp:seed_dispersal |
13q14
|
| gptkbp:social_responsibility |
gptkb:MRI
CT scan genetic testing ultrasound eye examination depends on early detection |
| gptkbp:symptoms |
vision problems
strabismus eye redness eye swelling white pupillary reflex |
| gptkbp:treatment |
gptkb:hospital
palliative care clinical trials supportive care radiation therapy chemotherapy laser therapy experimental treatments new drug therapies cryotherapy enucleation |
| gptkbp:bfsParent |
gptkb:sporadic_retinoblastoma
gptkb:retinoblastoma_protein_(Rb) gptkb:alveolar_rhabdomyosarcoma |
| gptkbp:bfsLayer |
4
|