Statements (51)
| Predicate | Object |
|---|---|
| gptkbp:instance_of |
gptkb:Genetics
|
| gptkbp:caused_by |
C1 inhibitor deficiency
|
| gptkbp:clinical_trial |
non-pitting edema
onset in childhood or adolescence recurrent episodes |
| gptkbp:complication |
asphyxiation
psychological impact gastrointestinal obstruction |
| gptkbp:condition |
acquired angioedema
|
| gptkbp:demographics |
affects all ethnic groups
affects both genders equally |
| gptkbp:diagnosis |
genetic testing
clinical evaluation can be life-threatening variable severity |
| gptkbp:educational_resources |
support groups
online forums medical journals patient brochures |
| gptkbp:first_described_by |
in the 19th century
|
| https://www.w3.org/2000/01/rdf-schema#label |
hereditary angioedema
|
| gptkbp:inherits_from |
autosomal dominant
|
| gptkbp:is_involved_in |
C1 Esterase Inhibitor Deficiency Foundation
Hereditary Angioedema Association |
| gptkbp:management |
avoidance of triggers
emergency treatment |
| gptkbp:originated_in |
PLG
F12 C1 NH |
| gptkbp:prevalence |
1 in 50,000 to 1 in 150,000
|
| gptkbp:public_awareness |
National Angioedema Awareness Day
World Allergy Week |
| gptkbp:research_focus |
gptkb:gene_therapy
new medications improved diagnostics |
| gptkbp:risk_factor |
gptkb:surgery
stress trauma hormonal changes family history |
| gptkbp:symptoms |
abdominal pain
swelling difficulty breathing skin rash |
| gptkbp:treatment |
antifibrinolytics
C1 inhibitor replacement therapy bradykinin receptor antagonists |
| gptkbp:bfsParent |
gptkb:Stanozolol
gptkb:Lanadelumab gptkb:Cinryze |
| gptkbp:bfsLayer |
6
|