Statements (58)
| Predicate | Object |
|---|---|
| gptkbp:instance_of |
gptkb:healthcare_organization
|
| gptkbp:advocates_for |
gptkb:Retinoblastoma_International
gptkb:American_Childhood_Cancer_Organization |
| gptkbp:affects |
gptkb:Person
educational challenges secondary cancers fertility issues psychological impact social integration issues |
| gptkbp:aftermath |
vision problems
psychosocial challenges |
| gptkbp:age |
infancy
|
| gptkbp:associated_with |
gptkb:bilateral_retinoblastoma
gptkb:unilateral_retinoblastoma other cancers |
| gptkbp:availability |
gptkb:battle
|
| gptkbp:caused_by |
R B1 gene mutation
|
| gptkbp:clinical_trial |
ongoing
|
| gptkbp:counseling_services |
for affected families
|
| gptkbp:descendant |
autosomal dominant
|
| gptkbp:expansion_plans |
genetic risk assessment
|
| gptkbp:first_described_by |
1930s
|
| gptkbp:genetic_diversity |
germline mutation
for at-risk family members for early intervention |
| https://www.w3.org/2000/01/rdf-schema#label |
familial retinoblastoma
|
| gptkbp:is_popular_in |
rare
|
| gptkbp:provides_information_on |
NCCN guidelines
ACOG guidelines |
| gptkbp:public_awareness |
gptkb:Retinoblastoma_Awareness_Month
|
| gptkbp:research |
importance of surveillance
age of onset variability impact of treatment on quality of life increased risk of other tumors variable penetrance |
| gptkbp:research_focus |
gptkb:physicist
targeted therapy early detection methods |
| gptkbp:risk_factor |
family history
|
| gptkbp:screenings |
annual exams
early eye exams |
| gptkbp:social_responsibility |
genetic testing
good with early detection |
| gptkbp:symptoms |
vision loss
strabismus eye redness eye swelling tumors in one or both eyes white pupillary reflex |
| gptkbp:treatment |
gptkb:hospital
radiation therapy chemotherapy laser therapy vitrectomy cryotherapy enucleation |
| gptkbp:bfsParent |
gptkb:healthcare_organization
|
| gptkbp:bfsLayer |
3
|