early onset Alzheimer's disease
GPTKB entity
Statements (66)
| Predicate | Object |
|---|---|
| gptkbp:instance_of |
gptkb:psychologist
|
| gptkbp:advocates_for |
gptkb:Alzheimer's_Association
policy changes research funding |
| gptkbp:affects |
younger individuals
|
| gptkbp:age |
before age 65
|
| gptkbp:clinical_trial |
cognitive decline
sleep disturbances disorientation apathy behavioral changes hallucinations neurodegeneration delusions agitation difficulty with time management difficulty recognizing faces loss of initiative language difficulties loss of empathy difficulty following conversations difficulty with abstract thinking difficulty with decision making difficulty with numbers difficulty with planning and organizing executive function impairment inability to perform familiar tasks misplacing things plaques and tangles repetition of questions or statements visual-spatial issues |
| gptkbp:current_use |
gptkb:frontotemporal_dementia
mild cognitive impairment |
| gptkbp:genetic_diversity |
APP gene mutation
PSE N1 gene mutation PSE N2 gene mutation |
| https://www.w3.org/2000/01/rdf-schema#label |
early onset Alzheimer's disease
|
| gptkbp:impact |
social relationships
financial planning daily living activities emotional well-being work and career |
| gptkbp:is_popular_in |
less than 5% of Alzheimer's cases
|
| gptkbp:number_of_teams |
can be rapid
|
| gptkbp:personal_life |
healthy diet may help
cognitive engagement may help physical activity may help sleep quality may affect progression social interaction may help |
| gptkbp:public_awareness |
increased public awareness needed
|
| gptkbp:research_focus |
biomarkers
clinical trials |
| gptkbp:risk_factor |
family history
genetic predisposition |
| gptkbp:social_responsibility |
brain imaging
neuropsychological testing |
| gptkbp:supports |
counseling services
caregiver support groups |
| gptkbp:symptoms |
memory loss
difficulty in planning changes in mood and personality confusion with time or place |
| gptkbp:treatment |
cholinesterase inhibitors
memantine |
| gptkbp:bfsParent |
gptkb:Down_syndrome
|
| gptkbp:bfsLayer |
4
|