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gptkbp:instance_of
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gptkb:Genetics
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|
gptkbp:advocacy
|
active
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gptkbp:affects
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immune system
|
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gptkbp:associated_with
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catalase-positive bacteria
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gptkbp:caused_by
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mutation in the CYBB gene
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gptkbp:clinical_trial
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gptkb:pneumonia
ongoing
eczema
failure to thrive
skin infections
hepatosplenomegaly
osteomyelitis
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gptkbp:complications
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gptkb:disease
gptkb:Oncology
abscesses
|
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gptkbp:condition
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gptkb:Chronic_Granulomatous_Disease
gptkb:immunotherapy
gptkb:Hyper-Ig_E_syndrome
|
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gptkbp:diagnosis
|
blood tests
family history
clinical history
laboratory findings
|
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gptkbp:first_described_by
|
1950s
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gptkbp:gender_predominance
|
male
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gptkbp:genetic_studies
|
available
recommended
important for families
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
X-linked Chronic Granulomatous Disease
|
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gptkbp:inherits_from
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X-linked recessive
|
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gptkbp:is_involved_in
|
available
|
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gptkbp:lifespan
|
variable
|
|
gptkbp:pathway
|
defective NADPH oxidase
|
|
gptkbp:prevalence
|
rare
|
|
gptkbp:public_awareness
|
ongoing
|
|
gptkbp:registration
|
available
|
|
gptkbp:research_focus
|
gptkb:gene_therapy
gptkb:immunotherapy
new antibiotics
|
|
gptkbp:research_institutes
|
focused on infectious diseases
focused on genetics
focused on immunology
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gptkbp:symptoms
|
recurrent infections
granuloma formation
|
|
gptkbp:treatment
|
gptkb:gene_therapy
gptkb:interferon-gamma
antibiotics
hematopoietic stem cell transplantation
prophylactic antibiotics
surgery for abscesses
|
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gptkbp:bfsParent
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gptkb:CYBA
|
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gptkbp:bfsLayer
|
6
|