Statements (67)
| Predicate | Object |
|---|---|
| gptkbp:instance_of |
gptkb:DNA
|
| gptkbp:associated_with |
spliceosomal complex
|
| gptkbp:composed_of |
U2 RNA
protein components |
| gptkbp:contains |
U2 sn RNA
|
| gptkbp:discovered_by |
researchers studying RNA splicing
|
| gptkbp:financial_stability |
protein-protein interactions
|
| gptkbp:function |
splicing of pre-m RNA
|
| gptkbp:has_role |
gene expression regulation
|
| https://www.w3.org/2000/01/rdf-schema#label |
U2 sn RNP
|
| gptkbp:interacts_with |
U1 sn RNP
U4/ U6 sn RNP |
| gptkbp:involved_in |
m RNA processing
|
| gptkbp:is_associated_with |
cellular signaling pathways
m RNA stability RNA splicing factors spliceosomal assembly spliceosomal dynamics |
| gptkbp:is_characterized_by |
specific RNA sequences
specific binding affinities specific protein composition specific protein interactions specific structural features |
| gptkbp:is_essential_for |
cell viability
cellular homeostasis protein synthesis cellular differentiation m RNA maturation pre-m RNA splicing |
| gptkbp:is_expressed_in |
various tissues
|
| gptkbp:is_found_in |
gptkb:Atom
|
| gptkbp:is_involved_in |
RNA metabolism
cell cycle regulation cellular response to stress transcription regulation RNA transport alternative splicing protein-protein interactions RNA editing gene splicing post-transcriptional regulation RNA processing pathways RNA splicing regulation |
| gptkbp:is_linked_to |
gptkb:neurodegenerative_diseases
genetic disorders autoimmune diseases cancer research various diseases |
| gptkbp:is_part_of |
RNA splicing machinery
nuclear speckles RNA splicing complexes RNA-protein complexes molecular complexes nuclear RNA processing machinery |
| gptkbp:is_recognized_by |
eukaryotic cells
|
| gptkbp:is_regulated_by |
cellular signaling pathways
|
| gptkbp:is_studied_for |
therapeutic interventions
biomedical research therapeutic applications |
| gptkbp:is_studied_in |
molecular biology
clinical research genetic research |
| gptkbp:part_of |
gptkb:spliceosome
|
| gptkbp:requires |
ATP for function
|
| gptkbp:targets |
antiviral therapies
|
| gptkbp:bfsParent |
gptkb:SF3_B1
|
| gptkbp:bfsLayer |
6
|