Statements (54)
| Predicate | Object |
|---|---|
| gptkbp:instance_of |
gptkb:psychologist
|
| gptkbp:affects |
brain function
|
| gptkbp:allows |
infectious agents
|
| gptkbp:associated_with |
genetic mutations
infected tissue consumption |
| gptkbp:caused_by |
prions
|
| gptkbp:healthcare |
gptkb:theorem
|
| gptkbp:historical_significance |
first recognized in sheep
impact on livestock industry increased awareness in the 1990s influence on food safety regulations linked to scrapie |
| https://www.w3.org/2000/01/rdf-schema#label |
The Prion Diseases
|
| gptkbp:includes |
gptkb:Kuru
Bovine spongiform encephalopathy Creutzfeldt-Jakob disease Fatal familial insomnia Gerstmann-Sträussler-Scheinker syndrome |
| gptkbp:incubation_period |
years
|
| gptkbp:is_characterized_by |
abnormal protein folding
|
| gptkbp:is_linked_to |
environmental factors
cannibalism variant Creutzfeldt-Jakob disease animal husbandry practices genetic predisposition blood transfusions mad cow disease infected surgical instruments prion-like mechanisms in other diseases |
| gptkbp:is_recognized_by |
1950s
|
| gptkbp:research_focus |
diagnostic methods
treatment options prion protein structure transmission pathways |
| gptkbp:resulted_in |
neurodegeneration
|
| gptkbp:social_responsibility |
rare
MRI scans geographically distributed brain biopsy CSF analysis affecting both genders |
| gptkbp:symptoms |
seizures
memory loss difficulty speaking muscle stiffness movement disorders personality changes visual disturbances incoordination severe insomnia |
| gptkbp:treatment |
gptkb:theorem
supportive care |
| gptkbp:bfsParent |
gptkb:Karl_Gajdusek
|
| gptkbp:bfsLayer |
5
|