Statements (61)
| Predicate | Object |
|---|---|
| gptkbp:instance_of |
gptkb:protein
|
| gptkbp:can_elicit |
T-cell responses
|
| gptkbp:components |
viral envelope
recombinant proteins |
| gptkbp:composed_of |
S1 and S2 subunits
|
| gptkbp:function |
facilitates entry of the virus into host cells
|
| gptkbp:has_a_focus_on |
epidemiological studies
public health research therapeutic research molecular studies |
| gptkbp:has_role |
viral fusion with host cell membrane
|
| https://www.w3.org/2000/01/rdf-schema#label |
SARS-Co V-2 spike protein
|
| gptkbp:is_a_subject_of |
clinical trials
biomedical research genetic sequencing studies |
| gptkbp:is_analyzed_in |
cryogenic electron microscopy
|
| gptkbp:is_associated_with |
variant strains
immune evasion vaccine breakthrough infections immune response variability |
| gptkbp:is_essential_for |
vaccine efficacy
viral infectivity |
| gptkbp:is_expressed_in |
viral replication
infected cells |
| gptkbp:is_involved_in |
immune response
antigen presentation cell signaling pathways pathogen recognition viral pathogenesis viral entry mechanisms host immune evasion viral assembly viral shedding viral load determination |
| gptkbp:is_linked_to |
long COVID symptoms
disease severity transmissibility rates viral fitness. |
| gptkbp:is_recognized_by |
neutralizing antibodies
|
| gptkbp:is_studied_for |
antiviral drug development
vaccine development therapeutic antibodies vaccine safety public health strategies vaccine formulation |
| gptkbp:is_studied_in |
structural biology
|
| gptkbp:is_targeted_at |
COVID-19 vaccines
|
| gptkbp:is_used_in |
diagnostic tests
|
| gptkbp:knockouts |
ACE2 receptor
|
| gptkbp:location |
on the surface of the virus
|
| gptkbp:modifications |
glycosylation
|
| gptkbp:occurs_in |
mutations
|
| gptkbp:targets |
therapeutic interventions
monoclonal antibodies vaccine design broadly neutralizing antibodies vaccine boosters |
| gptkbp:trigger_type |
cytokine release
|
| gptkbp:was_a_factor_in |
transmission dynamics
|
| gptkbp:bfsParent |
gptkb:Cure_Vac_CVn_Co_V
|
| gptkbp:bfsLayer |
5
|