Statements (78)
| Predicate | Object |
|---|---|
| gptkbp:instance_of |
gptkb:protein
|
| gptkbp:associated_with |
cancer progression
|
| gptkbp:breeding_season |
other species
|
| gptkbp:code |
SARA gene on chromosome 1
|
| gptkbp:community |
gene expression
|
| gptkbp:contains |
SMAD-binding domain
|
| gptkbp:discovered_by |
gptkb:mythological_figure
|
| gptkbp:established |
apoptosis
|
| gptkbp:function |
regulates TGF-beta signaling
|
| gptkbp:has_role |
immune response
|
| https://www.w3.org/2000/01/rdf-schema#label |
SARA protein
|
| gptkbp:interacts_with |
Smad proteins
|
| gptkbp:is_aimed_at |
therapeutic agents
|
| gptkbp:is_associated_with |
tumor suppression
|
| gptkbp:is_essential_for |
early embryonic development
|
| gptkbp:is_involved_in |
gptkb:embryonic_development
cell cycle regulation cell differentiation cellular homeostasis cellular metabolism cellular stress response signal transduction wound healing muscle development fibrosis cellular differentiation extracellular matrix remodeling developmental biology tissue regeneration neurogenesis angiogenesis immune cell activation inflammatory response tissue repair cell adhesion cell migration metastasis cellular signaling pathways cellular communication stem cell maintenance tissue homeostasis cellular repair mechanisms endothelial cell function neural crest development cellular signaling networks cellular responses to stress cellular responses to DNA damage cellular responses to cytokines cellular responses to environmental changes cellular responses to growth factors cellular responses to hormones cellular responses to infection cellular responses to injury cellular responses to mechanical stress cellular responses to oxidative stress cellular responses to nutrients cellular responses to hypoxia cellular responses to metabolic stress cellular responses to chemical stress cellular responses to radiation. cellular responses to thermal stress |
| gptkbp:is_known_for |
influence stem cell fate
|
| gptkbp:is_linked_to |
metabolic disorders
|
| gptkbp:is_part_of |
protein complexes
TGF-beta signaling pathway |
| gptkbp:is_represented_in |
various tissues
cardiac tissue embryonic stem cells |
| gptkbp:is_studied_in |
cancer research
|
| gptkbp:location |
cytoplasm
|
| gptkbp:promoter |
SARA gene
|
| gptkbp:regulates |
cell growth
growth factors micro RN As |
| gptkbp:type |
signaling protein
|
| gptkbp:weight |
approximately 50 k Da
|
| gptkbp:bfsParent |
gptkb:TGF-beta_receptor_type_I
|
| gptkbp:bfsLayer |
8
|