Statements (53)
| Predicate | Object |
|---|---|
| gptkbp:instance_of |
gptkb:pharmaceuticals
|
| gptkbp:approves |
gptkb:1963
|
| gptkbp:available_on |
generic
|
| gptkbp:brand |
gptkb:Rheumatrex
gptkb:Trexall |
| gptkbp:class |
gptkb:oppression
|
| gptkbp:contains |
gptkb:methotrexate
|
| gptkbp:contraindication |
alcoholism
liver disease pregnancy |
| gptkbp:dosage_form |
gptkb:tablet
|
| gptkbp:formulation |
oral tablet
|
| https://www.w3.org/2000/01/rdf-schema#label |
Rheumatrex Dose Pack
|
| gptkbp:indication |
gptkb:cancer_treatment
autoimmune diseases psoriasis treatment |
| gptkbp:ingredients |
gptkb:methotrexate
|
| gptkbp:interacts_with |
NSAIDs
live vaccines penicillins sulfonamides |
| gptkbp:is_monitored_by |
liver function tests
renal function complete blood count |
| gptkbp:lifespan |
3 to 10 hours
|
| gptkbp:manufacturer |
various manufacturers
|
| gptkbp:mechanism_of_action |
inhibits dihydrofolate reductase
|
| gptkbp:packaging |
blister pack
|
| gptkbp:patient_education |
avoid alcohol
stay hydrated report unusual bleeding avoid live vaccines regular lab tests required |
| gptkbp:requires |
gptkb:true
|
| gptkbp:rounds |
renal
|
| gptkbp:route_of_administration |
oral
|
| gptkbp:side_effect |
fatigue
nausea liver toxicity skin reactions neurotoxicity pulmonary toxicity mouth sores gastrointestinal toxicity |
| gptkbp:storage |
room temperature
|
| gptkbp:suitable_for |
active infections
severe renal impairment bone marrow suppression |
| gptkbp:used_for |
treatment of certain cancers
treatment of psoriasis treatment of rheumatoid arthritis |
| gptkbp:bfsParent |
gptkb:methotrexate
|
| gptkbp:bfsLayer |
5
|