RNA polymerase II transcription initiation complex
GPTKB entity
Statements (69)
| Predicate | Object |
|---|---|
| gptkbp:instance_of |
gptkb:DNA
|
| gptkbp:composed_of |
gptkb:RNA_polymerase_II
|
| gptkbp:dependency |
nucleotides
|
| gptkbp:form |
pre-initiation complex
|
| https://www.w3.org/2000/01/rdf-schema#label |
RNA polymerase II transcription initiation complex
|
| gptkbp:initiated_by |
repressors
co-activators |
| gptkbp:interacts_with |
transcription factors
|
| gptkbp:involved_in |
gene expression
|
| gptkbp:is_associated_with |
chromatin remodeling
nuclear processes nuclear architecture gene transcription RNA polymerase II transcription RNA polymerase II activity nuclear RNA processing. |
| gptkbp:is_characterized_by |
phosphorylation of the C-terminal domain
|
| gptkbp:is_critical_for |
developmental processes
cellular function cellular communication |
| gptkbp:is_essential_for |
transcription
cellular differentiation |
| gptkbp:is_found_in |
eukaryotic cells
|
| gptkbp:is_influenced_by |
environmental factors
cell signaling pathways transcriptional activators |
| gptkbp:is_involved_in |
RNA splicing
cell cycle regulation cellular homeostasis cellular metabolism cellular stress response gene regulation protein synthesis cellular proliferation RNA processing cellular signaling pathways cellular signaling transcription termination transcriptional regulation RNA editing cellular repair mechanisms cellular differentiation processes cellular response to stimuli polyadenylation m RNA capping m RNA transport |
| gptkbp:is_linked_to |
cellular aging
epigenetic modifications disease mechanisms transcriptional fidelity |
| gptkbp:is_part_of |
RNA synthesis
RNA polymerase II complex transcription machinery gene regulatory networks eukaryotic transcription process |
| gptkbp:is_regulated_by |
post-translational modifications
chromatin structure enhancers nuclear factors |
| gptkbp:is_studied_in |
molecular biology
|
| gptkbp:is_targeted_at |
drugs
|
| gptkbp:knockouts |
gptkb:DNA
|
| gptkbp:produces |
pre-m RNA
|
| gptkbp:requires |
promoter region
general transcription factors |
| gptkbp:synthesizes |
m RNA
|
| gptkbp:translocates |
along the DNA strand
|
| gptkbp:bfsParent |
gptkb:TFIID
|
| gptkbp:bfsLayer |
7
|