RET gene mutation

GPTKB entity

Statements (62)
Predicate Object
gptkbp:instance_of gptkb:physicist
gptkbp:affects neuroendocrine tissues
gptkbp:analyzes therapeutic interventions
genetic counseling
longitudinal studies
gptkbp:associated_with gptkb:medullary_thyroid_carcinoma
gptkb:pheochromocytoma
multiple endocrine neoplasia type 2
gptkbp:can_be tumor formation
gptkbp:can_lead_to cancer development
gptkbp:caused_by hypertension
abnormal cell signaling
gptkbp:demographics familial cases
gptkbp:descendant gptkb:Person
gptkbp:discovered_by 1990s
gptkbp:examines genetic epidemiology
molecular genetics
oncology research
https://www.w3.org/2000/01/rdf-schema#label RET gene mutation
gptkbp:investment gptkb:healthcare_organization
gptkbp:is_aimed_at specific drugs
gptkbp:is_analyzed_in biomarker research
clinical trials for therapies
gptkbp:is_associated_with increased surveillance
autosomal dominant inheritance
early onset of disease
prophylactic surgery
gptkbp:is_considered a risk factor
a hereditary condition
a significant finding
gptkbp:is_documented_in gptkb:municipality
gptkb:academic_journal
gptkbp:is_evaluated_by prognosis
treatment outcomes
gptkbp:is_found_in chromosome 10
gptkbp:is_linked_to genetic predisposition
tumor suppressor genes
germline mutations
RET signaling pathway
RET protein function
gptkbp:is_monitored_by oncologists
gptkbp:is_often_used_in certain populations
gptkbp:is_part_of personalized medicine
cancer risk assessment
cancer genetics
cancer prevention strategies
cancer predisposition syndromes
gptkbp:is_recognized_by familial medullary thyroid carcinoma
familial syndromes
gptkbp:is_related_to endocrine tumors
RET proto-oncogene
gptkbp:is_studied_in clinical trials
risk management strategies
therapeutic targets
gptkbp:recognizes DNA sequencing
gptkbp:social_responsibility genetic testing
gptkbp:treatment gptkb:hospital
chemotherapy
targeted therapy
hormone therapy
gptkbp:bfsParent gptkb:multiple_endocrine_neoplasia_syndrome_type_2
gptkbp:bfsLayer 5