Statements (62)
Predicate | Object |
---|---|
gptkbp:instance_of |
gptkb:physicist
|
gptkbp:affects |
neuroendocrine tissues
|
gptkbp:analyzes |
therapeutic interventions
genetic counseling longitudinal studies |
gptkbp:associated_with |
gptkb:medullary_thyroid_carcinoma
gptkb:pheochromocytoma multiple endocrine neoplasia type 2 |
gptkbp:can_be |
tumor formation
|
gptkbp:can_lead_to |
cancer development
|
gptkbp:caused_by |
hypertension
abnormal cell signaling |
gptkbp:demographics |
familial cases
|
gptkbp:descendant |
gptkb:Person
|
gptkbp:discovered_by |
1990s
|
gptkbp:examines |
genetic epidemiology
molecular genetics oncology research |
https://www.w3.org/2000/01/rdf-schema#label |
RET gene mutation
|
gptkbp:investment |
gptkb:healthcare_organization
|
gptkbp:is_aimed_at |
specific drugs
|
gptkbp:is_analyzed_in |
biomarker research
clinical trials for therapies |
gptkbp:is_associated_with |
increased surveillance
autosomal dominant inheritance early onset of disease prophylactic surgery |
gptkbp:is_considered |
a risk factor
a hereditary condition a significant finding |
gptkbp:is_documented_in |
gptkb:municipality
gptkb:academic_journal |
gptkbp:is_evaluated_by |
prognosis
treatment outcomes |
gptkbp:is_found_in |
chromosome 10
|
gptkbp:is_linked_to |
genetic predisposition
tumor suppressor genes germline mutations RET signaling pathway RET protein function |
gptkbp:is_monitored_by |
oncologists
|
gptkbp:is_often_used_in |
certain populations
|
gptkbp:is_part_of |
personalized medicine
cancer risk assessment cancer genetics cancer prevention strategies cancer predisposition syndromes |
gptkbp:is_recognized_by |
familial medullary thyroid carcinoma
familial syndromes |
gptkbp:is_related_to |
endocrine tumors
RET proto-oncogene |
gptkbp:is_studied_in |
clinical trials
risk management strategies therapeutic targets |
gptkbp:recognizes |
DNA sequencing
|
gptkbp:social_responsibility |
genetic testing
|
gptkbp:treatment |
gptkb:hospital
chemotherapy targeted therapy hormone therapy |
gptkbp:bfsParent |
gptkb:multiple_endocrine_neoplasia_syndrome_type_2
|
gptkbp:bfsLayer |
5
|