Statements (61)
| Predicate | Object |
|---|---|
| gptkbp:instance_of |
gptkb:Oncology
|
| gptkbp:affects |
B-lymphocytes
|
| gptkbp:associated_with |
genetic mutations
|
| gptkbp:can |
long-term effects
|
| gptkbp:can_be_used_to |
central nervous system involvement
|
| gptkbp:can_cause |
lymphadenopathy
|
| gptkbp:can_lead_to |
secondary malignancies
organomegaly bone marrow failure |
| gptkbp:can_result_in |
immunosuppression
|
| gptkbp:cause |
childhood cancer deaths
|
| gptkbp:caused_by |
chromosomal abnormalities
|
| gptkbp:diagnosis |
children and adolescents
cytogenetic analysis bone marrow biopsy |
| gptkbp:exhibits |
bleeding disorders
|
| gptkbp:has_achieved |
tumor lysis syndrome
|
| https://www.w3.org/2000/01/rdf-schema#label |
Precursor B-cell ALL
|
| gptkbp:is_associated_with |
gptkb:Down_syndrome
increased risk of infections viral infections autoimmune disorders poor prognosis in adults poor response to treatment in adults |
| gptkbp:is_characterized_by |
rapid onset of symptoms
high white blood cell count high levels of lymphoblasts lymphoblasts in the blood the presence of immature B-cell precursors the presence of specific genetic markers the proliferation of immature B-cells the presence of CD19 markers |
| gptkbp:is_common_in |
gptkb:children
|
| gptkbp:is_effective_against |
in nature
|
| gptkbp:is_influenced_by |
genetic predisposition
family history of leukemia |
| gptkbp:is_linked_to |
environmental factors
|
| gptkbp:is_monitored_by |
blood tests
side effects of treatment remission status |
| gptkbp:is_part_of |
the broader category of blood cancers
the group of leukemias |
| gptkbp:requires |
radiation therapy
stem cell transplant |
| gptkbp:scientific_classification |
subtypes
leukemias |
| gptkbp:symptoms |
fatigue
fever easy bruising pallor |
| gptkbp:treatment |
gptkb:immunotherapy
supportive care chemotherapy targeted therapy pediatric oncologists specialized cancer centers combination chemotherapy |
| gptkbp:type_of |
hematological malignancy
B-cell leukemia |
| gptkbp:bfsParent |
gptkb:B-cell_ALL
|
| gptkbp:bfsLayer |
5
|