Statements (43)
| Predicate | Object |
|---|---|
| gptkbp:instance_of |
gptkb:protein
|
| gptkbp:application |
apoptosis regulation
cell differentiation cell proliferation signal transduction endocytosis membrane trafficking biomarker for disease exocytosis target for drug development study of cellular processes investigation of phosphoinositide roles model for studying kinase activity study of cell signaling pathways |
| gptkbp:associated_with |
phosphoinositide metabolism
|
| gptkbp:clinical_trial |
associated with metabolic disorders
involved in cardiovascular diseases involved in neurodegenerative diseases potential target for cancer therapy role in immune response |
| gptkbp:enzyme_classification |
2.7.1.68
|
| gptkbp:function |
phosphatidylinositol phosphate kinase activity
|
| gptkbp:fuselage_material |
phosphatidylinositol 4-phosphate
|
| https://www.w3.org/2000/01/rdf-schema#label |
PIP5 K20
|
| gptkbp:interacts_with |
phosphatidylinositol 4-phosphate
|
| gptkbp:involved_in |
cell signaling
|
| gptkbp:is_expressed_in |
ubiquitous in tissues
|
| gptkbp:location |
cytoplasm
|
| gptkbp:orthologs |
gptkb:PIP5_K1_A
gptkb:PIP5_K1_B gptkb:PIP5_K2_A gptkb:PIP5_K2_B |
| gptkbp:pathway |
phosphatidylinositol signaling pathway
inositol phosphate metabolism |
| gptkbp:product |
phosphatidylinositol 5-phosphate
|
| gptkbp:promoter |
PIP5 K20 gene
|
| gptkbp:regulatory_compliance |
regulated by calcium ions
regulated by phosphatidic acid regulated by Rho GTPases |
| gptkbp:research |
ATP binding
kinase activity |
| gptkbp:bfsParent |
gptkb:PIK3_CA
|
| gptkbp:bfsLayer |
6
|