Statements (26)
| Predicate | Object |
|---|---|
| gptkbp:instance_of |
gptkb:biotechnology
|
| gptkbp:are |
used in studies of aging
a model for studying cardiovascular diseases a tool for studying genetic diseases created using CRISPR technology used to investigate cancer biology important for understanding host defense mechanisms important for studying the role of NCF1 in disease |
| gptkbp:associated_with |
immunology
|
| gptkbp:can_be |
crossbred with other mouse models
used to test new therapies |
| gptkbp:development |
autoimmune disorders
|
| gptkbp:exhibits |
altered inflammatory response
defective NADPH oxidase activity impaired neutrophil function |
| gptkbp:have |
altered cytokine profiles
been used in pharmacological studies mutations in NCF1 gene |
| https://www.w3.org/2000/01/rdf-schema#label |
NCF1 knockout mice
|
| gptkbp:is_studied_for |
oxidative stress
|
| gptkbp:model |
chronic granulomatous disease
|
| gptkbp:related_show |
increased susceptibility to infections
reduced reactive oxygen species production |
| gptkbp:used_in |
gptkb:research
|
| gptkbp:bfsParent |
gptkb:NCF1
|
| gptkbp:bfsLayer |
8
|