Statements (53)
| Predicate | Object |
|---|---|
| gptkbp:instance_of |
gptkb:disease
|
| gptkbp:affects |
plasma cells
|
| gptkbp:can_be_asymptomatic_for |
years
|
| gptkbp:can_be_used_to |
elevated serum protein levels
|
| gptkbp:can_cause |
bone pain
|
| gptkbp:can_detect |
immunofixation electrophoresis
|
| gptkbp:can_lead_to |
secondary malignancies
hyperviscosity syndrome |
| gptkbp:can_progress_to |
malignant diseases
|
| gptkbp:condition |
can be hereditary in some cases
can be managed with lifestyle changes can be monitored over time can be stable for years may require specialist referral may require treatment if progression occurs requires clinical evaluation |
| gptkbp:diagnosis |
serum protein electrophoresis
approximately 3% of the population over 50 bone marrow biopsy if needed |
| https://www.w3.org/2000/01/rdf-schema#label |
MGUS
|
| gptkbp:is_a_benign_condition |
gptkb:true
|
| gptkbp:is_associated_with |
increased risk of infections
renal impairment neuropathy |
| gptkbp:is_characterized_by |
monoclonal gammopathy
low levels of monoclonal protein |
| gptkbp:is_common_in |
older adults
|
| gptkbp:is_considered |
a cancer
|
| gptkbp:is_evaluated_by |
changes in clinical status
|
| gptkbp:is_linked_to |
chronic inflammatory conditions
|
| gptkbp:is_monitored_by |
regular blood tests
hematologists changes in protein levels |
| gptkbp:is_not_associated_with |
significant organ damage
|
| gptkbp:is_not_treated_unless |
symptoms develop
|
| gptkbp:is_often_asymptomatic |
gptkb:true
|
| gptkbp:is_often_described_as |
monoclonal gammopathy of undetermined significance
|
| gptkbp:is_often_discovered_during |
routine blood tests
|
| gptkbp:is_often_seen_in |
gptkb:Oncology
African American population patients with other hematological disorders |
| gptkbp:is_related_to |
autoimmune disorders
chronic infections |
| gptkbp:replaced_by |
gptkb:true
|
| gptkbp:requires_follow-up |
every 6 to 12 months
|
| gptkbp:risk_factor |
gptkb:Waldenström's_macroglobulinemia
gptkb:Oncology |
| gptkbp:scientific_classification |
Ig G, Ig A, and Ig M types
|
| gptkbp:treatment |
observation
|
| gptkbp:type_of |
plasma cell disorder
|
| gptkbp:was_a_precursor_to |
gptkb:smoldering_multiple_myeloma
|
| gptkbp:bfsParent |
gptkb:Multiple_Myeloma
|
| gptkbp:bfsLayer |
7
|