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gptkbp:instance_of
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gptkb:chemical_compound
|
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gptkbp:can_be_used_to_modify
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aromatic compounds
|
|
gptkbp:can_create
|
multiple products
branched alkyl groups
linear alkyl groups
|
|
gptkbp:can_lead_to
|
polyalkylation
aromatic hydrocarbons
|
|
gptkbp:design
|
hydrolysis
|
|
gptkbp:has_limitations
|
carbocation stability
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Friedel– Crafts alkylation
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gptkbp:involves
|
alkyl halide
|
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gptkbp:is_a_reaction_that_can_be_affected_by
|
pressure
temperature
concentration of reactants
|
|
gptkbp:is_a_reaction_that_can_be_monitored_by
|
NMR spectroscopy
GC-MS
|
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gptkbp:is_a_reaction_that_can_be_optimized_for
|
selectivity
yield
|
|
gptkbp:is_a_reaction_that_can_be_performed_in
|
solvent-free conditions
|
|
gptkbp:is_a_reaction_that_can_be_performed_under
|
anhydrous conditions
|
|
gptkbp:is_a_reaction_that_can_be_performed_with
|
various alkyl groups
|
|
gptkbp:is_a_reaction_that_can_be_scaled_up_for
|
industrial applications
|
|
gptkbp:is_a_reaction_that_can_produce
|
complex mixtures
|
|
gptkbp:is_a_reaction_that_involves
|
nucleophiles
electrophiles
|
|
gptkbp:is_affected_by
|
reaction conditions
|
|
gptkbp:is_often_accompanied_by
|
deprotection steps
|
|
gptkbp:is_often_used_in
|
gptkb:pharmaceuticals
polymer chemistry
|
|
gptkbp:is_often_used_to_synthesize
|
alkyl-substituted aromatics
|
|
gptkbp:is_used_in
|
organic synthesis
|
|
gptkbp:key_feature
|
aromatic chemistry
|
|
gptkbp:named_after
|
gptkb:Charles_Friedel
James Crafts
|
|
gptkbp:performed_by
|
benzene
naphthalene
toluene
|
|
gptkbp:produces
|
alkylated aromatic compound
|
|
gptkbp:requires
|
Lewis acid catalyst
|
|
gptkbp:sensitivity
|
steric effects
|
|
gptkbp:suitable_for
|
deactivated aromatic rings
|
|
gptkbp:type
|
electrophilic aromatic substitution
|
|
gptkbp:type_of
|
substitution reaction
|
|
gptkbp:was_a_catalyst_for
|
BF3
Al Cl3
|
|
gptkbp:was_a_response_to
|
synthesis of fragrances
synthesis of agrochemicals
synthesis of dyes
synthesis of polymers
|
|
gptkbp:bfsParent
|
gptkb:Friedel–_Crafts_acylation
|
|
gptkbp:bfsLayer
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8
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