Corynebacterium diphtheriae
E928055
Corynebacterium diphtheriae is a Gram-positive, toxin-producing bacterium that causes the infectious disease diphtheria in humans.
All labels observed (1)
| Label | Occurrences |
|---|---|
| Corynebacterium diphtheriae canonical | 4 |
How this entity was disambiguated
This entity first appeared as the object of triple T11466553 — resolving that mention is where its identity was fixed. The disambiguator weighed these candidate entities and picked the highlighted one (or “None”, minting a new entity). This is how homonymy is resolved: the same surface form can point to different entities.
NED1
Entity disambiguation (via context triple)
gpt-5-mini-2025-08-07
Target entity: Corynebacterium diphtheriae Context triple: [Corynebacteriales, includesPathogen, Corynebacterium diphtheriae]
-
A.
Bacillus anthracis
Bacillus anthracis is a Gram-positive, spore-forming bacterium that causes the disease anthrax in humans and animals.
-
B.
Yersinia pestis
Yersinia pestis is a highly virulent bacterium responsible for plague, including the historic pandemics of bubonic, septicemic, and pneumonic forms.
-
C.
Yersinia
Yersinia is a genus of Gram-negative bacteria that includes several pathogenic species, most notably Yersinia pestis, the causative agent of plague.
-
D.
Bacillus
Bacillus is a genus of rod-shaped, endospore-forming bacteria that includes both harmless environmental species and notable pathogens such as Bacillus anthracis.
-
E.
Vibrio cholerae
Vibrio cholerae is a Gram-negative, comma-shaped bacterium that causes the acute diarrheal disease cholera in humans.
- F. None of above. chosen
- G. Unsure - the case is ambiguous/there is not enough information to decide.
NED2
Entity disambiguation (via description)
gpt-5-mini-2025-08-07
Target entity: Corynebacterium diphtheriae Target entity description: Corynebacterium diphtheriae is a Gram-positive, toxin-producing bacterium that causes the infectious disease diphtheria in humans.
-
A.
Bacillus anthracis
Bacillus anthracis is a Gram-positive, spore-forming bacterium that causes the disease anthrax in humans and animals.
-
B.
Yersinia pestis
Yersinia pestis is a highly virulent bacterium responsible for plague, including the historic pandemics of bubonic, septicemic, and pneumonic forms.
-
C.
Yersinia
Yersinia is a genus of Gram-negative bacteria that includes several pathogenic species, most notably Yersinia pestis, the causative agent of plague.
-
D.
Bacillus
Bacillus is a genus of rod-shaped, endospore-forming bacteria that includes both harmless environmental species and notable pathogens such as Bacillus anthracis.
-
E.
Vibrio cholerae
Vibrio cholerae is a Gram-negative, comma-shaped bacterium that causes the acute diarrheal disease cholera in humans.
- F. None of above. chosen
Statements (52)
| Predicate | Object |
|---|---|
| instanceOf |
bacterial species
ⓘ
pathogenic bacterium ⓘ |
| arrangement |
Chinese-letter pattern
ⓘ
palisades ⓘ |
| catalaseActivity | catalase-positive ⓘ |
| causes | diphtheria ⓘ |
| cellMorphology | club-shaped rods ⓘ |
| cellWallComponent | mycolic acids ⓘ |
| class | Actinobacteria ⓘ |
| clinicalManifestation |
bull neck
ⓘ
pseudomembrane formation in throat ⓘ |
| complication |
airway obstruction
ⓘ
myocarditis ⓘ peripheral neuropathy ⓘ |
| cultureMedium |
Loeffler medium
ⓘ
potassium tellurite agar ⓘ |
| diagnosticTest |
Elek test
ⓘ
PCR for tox gene ⓘ |
| domain | Bacteria ⓘ |
| family |
Corynebacteriaceae
ⓘ
linked to:
Corynebacteriales
|
| firstDescribedBy | Edwin Klebs ⓘ |
| genus | Corynebacterium ⓘ |
| gramStain | Gram-positive ⓘ |
| host | humans ⓘ |
| motility | non-motile ⓘ |
| order | Corynebacteriales ⓘ |
| oxygenRequirement | facultative anaerobe ⓘ |
| pathogenesisMechanism | inhibition of host protein synthesis ⓘ |
| phylum |
Actinobacteriota
ⓘ
linked to:
Actinomycetota
|
| preventedBy |
DTP vaccine
ⓘ
linked to:
Tdap vaccine
DTaP vaccine ⓘ Tdap vaccine ⓘ |
| primaryInfectionSite |
pharynx
ⓘ
tonsils ⓘ upper respiratory tract ⓘ |
| shape | rod-shaped ⓘ |
| sporeFormation | non-spore-forming ⓘ |
| stain |
Albert stain
ⓘ
Neisser stain ⓘ |
| stainingCharacteristic | metachromatic granules ⓘ |
| targetMolecule | elongation factor 2 ⓘ |
| taxonRank | species ⓘ |
| toxinActivity | ADP-ribosylation of EF-2 ⓘ |
| toxinGene | tox gene ⓘ |
| toxinGeneLocation | lysogenic bacteriophage ⓘ |
| toxinType | A-B exotoxin ⓘ |
| transmissionRoute |
close person-to-person contact
ⓘ
contaminated fomites ⓘ respiratory droplets ⓘ |
| vaccineTarget | diphtheria toxoid ⓘ |
| virulenceFactor | diphtheria toxin ⓘ |
| yearDescribed | 1884 ⓘ |
How these facts were elicited
The pipeline generated the facts above by prompting gpt-5.1 with this entity's name + description and the instruction below.
Instruction
You are a knowledge base construction expert. Given a subject entity and a description of it, return factual statements that you know for the subject as a JSON list of dictionaries(triples), where keys must be "subject", "predicate" and "object". The number of facts may be very high, between 25 to 50 or more, for very popular subjects. For less popular subjects, the number of facts can be very low, like 5 or 10. # Requirements - If you don't know the subject at all, return an empty list. - If the subject is not a named entity, return an empty list. - Include at least one triple where predicate is "instanceOf". - Do not get too wordy. - Separate several objects into multiple triples with one object.
Input
Subject: Corynebacterium diphtheriae Description of subject: Corynebacterium diphtheriae is a Gram-positive, toxin-producing bacterium that causes the infectious disease diphtheria in humans.
Referenced by (4)
Full triples — surface form annotated when it differs from this entity's canonical label.