bursa of Fabricius in birds

E902893

The bursa of Fabricius in birds is a specialized lymphoid organ near the cloaca that plays a crucial role in the development and maturation of B lymphocytes in avian species.

All labels observed (1)

Label Occurrences
bursa of Fabricius in birds canonical 1

How this entity was disambiguated

Statements (50)

Predicate Object
instanceOf avian organ
lymphoid tissue
primary lymphoid organ
absentIn amphibians
fish
mammals
reptiles
analogousFunctionTo bone marrow in mammals
cellTypeDeveloping B cells
connectedTo cloacal lumen
contains lymphocytes
macrophages
reticular epithelial cells
stromal cells
developmentalOrigin dorsal diverticulum of the cloaca
discoveredBy Hieronymus Fabricius
discoveryCentury 16th century
drainedBy lymphatic vessels
epitheliumType pseudostratified columnar epithelium
firstSiteOf B cell differentiation in birds
B cell repertoire formation in birds
function development of B lymphocytes
generation of antibody-producing cells
maturation of B lymphocytes
hasRegion follicular cortex
follicular medulla
mucosal folds
histologicalFeature bursa-associated lymphoid follicles
lesionEffect immunosuppression in birds
locatedIn birds
locatedNear cloaca
macroscopicAppearance sac-like diverticulum
namedAfter Hieronymus Fabricius
orientation dorsal to the cloaca
partOf avian immune system
presentInLifeStage juvenile birds
richIn lymphoid follicles
roleInImmunity diversification of immunoglobulin repertoire
humoral immunity
speciesExample chickens
ducks
pigeons
turkeys
susceptibleTo Gumboro disease
infectious bursal disease virus
undergoes involution at sexual maturity
usedIn immunological research
usedToStudy B cell ontogeny
avian immunology
vascularSupply branches of the cloacal artery

How these facts were elicited

Referenced by (1)

Full triples — surface form annotated when it differs from this entity's canonical label.

B lymphocytes nameDerivedFrom bursa of Fabricius in birds